vitalityPRO

Trans Resveratrol Powder

Trans-Resveratrol, in micronised powder form, is an antioxidant also believed to activate sirtuin genes responsible for activities most linked to longevity, such as DNA repair, metabolism, and stress response.

Features

  • 500mg per scoop
  • Take 1-2 scoops per day (scoop included)
  • Formulated with micronised Resveratrol, known for its superior bioavailability
  • Suitable for vegans 
  • Free from common allergens

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Third-Party Tested

Date • Batch # • Results

Purity results include Heavy Metals

Current Batch:

April 2026

•

2600064

Previous results:

June 2025

•

2500226, 2401062


September 2024

•

BN2300594


May 2023

•

TRES12012023


December 2022

•

T-RES12082022

GMP Certified Facility

Our supplements are manufactured in the UK, at facilities in Oxford and the North of England, following Good Manufacturing Practice (GMP) standards.

GMP sets requirements for hygiene, production, quality control, and traceability, helping ensure supplements are consistently manufactured under controlled conditions.

Our manufacturing partners hold independently issued GMP certificates. Rather than simply asking you to take our word for it, we've made these available below for you to review.

Our UK Manufacturers' GMP Certificates

Issued by Eurofins and SGS.

Manufacturer 1

Manufacturer 2

Manufacturer names have been redacted for commercial confidentiality.

ISO Quality Managed

Vitality Pro is independently certified to ISO 9001:2015, an internationally recognised standard for quality management systems.

Maintaining this certification requires ongoing monitoring, documented checks, regular reporting and independent audits. These processes help identify areas for improvement, ensure issues are addressed, and continually strengthen the systems and controls behind our supplements. It's a commitment to quality that must be demonstrated and maintained, not simply claimed.

We believe quality should be independently verified, not simply claimed. You can view our ISO 9001:2015 certificate below.

Our ISO 9001:2015 Certificate

View Our Certificate

Ingredients

View supplement label

Servings Per Container: 60 (30g) or 200 (100g)

Amount Per Serving Amount %NRV
Trans-Resveratrol 500mg *
Micronised from Japanese Knotweed, natural

Nutrient Reference Value not established*

Suitable for vegans. Contains no fillers, GMOs, common allergens, artificial colours, preservatives or flavours.

Storage & Stability

To maintain the potency and quality of your Resveratrol supplements, store them in a cool (20°C-25°C), dry place, and away from light. Trans-Resveratrol must not be exposed to light for long periods as it will degrade to Cis-Resveratrol. Please store your Resveratrol in a dark environment.

Quality Standards

Manufacturing: Our supplements are manufactured in the UK to Good Manufacturing Practice (GMP) standards. We also maintain an ISO 9001:2015-certified quality management system.

Independent batch testing: Every batch undergoes independent laboratory testing to verify quality, including purity. Testing is carried out by ISO 17025-accredited laboratories, including Certified Labs (formerly Micro Quality Labs).

We don't just make claims about quality. We publish the evidence. You can review our Certificates of Analysis on our product testing page.

Safety & Warnings

Do not exceed the recommended daily dose. Food supplements should not replace a varied and balanced diet and a healthy lifestyle. If you are pregnant, breastfeeding, under 18 or taking any medication, consult a doctor before use. Stop use if adverse reactions occur.

Interactions: Resveratrol is known to inhibit members of the Cytochrome P450 class of enzymes. As a result, it may interfere with antiplatelet and anticoagulant medications such as Warfarin. Additionally, resveratrol is classed as a phytoestrogen, a plant molecule that can mimic the effects of oestrogen in the body. Therefore, individuals who are hormone replacement therapies should therefore consult with their doctors before adding resveratrol to their longevity protocols. If you are taking these medications or any other medication, please first speak with your doctor before adding Resveratrol to your supplement regime.

For further information regarding any other potential drug and supplement interactions of Resveratrol please see the ingredient profile on Drug Bank.* Allergy: This product does not contain any common allergens; however, it should not be used by anyone with a history of hypersensitivity to its ingredients or those taking medications that may interact with it.

Pregnancy: If pregnant, consult your health professional before using this product.

*Drug Bank is an independent website that lists potential interactions between the ingredients in Trans-Resvertrol and other medications and supplements. It may not, however, list all known possible interactions. If you are on any medications or supplements you feel may interact negatively with Trans-Resvertrol please first speak with your doctor before using this product.

Reviews

1

Key Studies to Consider

While individual results may vary due to personal health conditions, genetics, and lifestyle choices, we guarantee that the supplements you receive are made with ingredients of the highest purity, similar to those used in scientific studies, to ensure maximum results.

Sirtuin Activator

*The below research, carried out by Dr David Sinclair and others, suggests that Resveratrol may enhance the activity of SIRT1 through several mechanisms, such as mimicking the effects of caloric restriction. The pathways and the extent of how effectively Resveratrol can activate SIRT1 remain a topic of ongoing investigation.

 Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan – Cell Study

Dosage: Not specified

Outcome: Increased lifespan and DNA stability in yeast

Summary: Resveratrol, which boosts NAD+ and activates sirtuins, extended the lifespan of yeast cells by 70%, similar to the effects of calorie restriction. This suggests that NAD+ and sirtuin activation could promote longevity.

Read more

 The Role and Mechanism of SIRT1 in Resveratrol-regulated Osteoblast Autophagy in Osteoporosis Rats – Animal study

Dosage: 5 mg/kg/day and 45 mg/kg/day resveratrol for 8 weeks

Outcome: Resveratrol improved bone density and promoted autophagy in bone cells through SIRT1 activation.

Summary: High-dose resveratrol activated SIRT1 and enhanced mitophagy in osteoblasts, protecting against bone loss in osteoporosis rats.

Read more

Longevity

*Sirtuin 1 is a molecule that when activated has been shown to increase lifespan in both cell and mouse studies. While Resveratrol is believed to work by activating this molecule there is still debate in the longevity community about its efficacy of this.

Resveratrol Improves Health and Survival of Mice on a High-Calorie Diet – Preclinical Animal Study

Dosage: Resveratrol (dosage not specified)

Outcome: Increased lifespan and improved health markers in mice fed a high-calorie diet

Summary: In middle-aged mice, resveratrol improved general health and increased lifespan, mimicking the benefits of a standard diet. This was noted through several markers including better insulin sensitivity, lower levels of certain ageing-related factors, more mitochondria (energy-producing structures in cells) and enhanced physical ability.

Read more

Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan – Cell Study

Dosage: Resveratrol, a compound found in red wine

Outcome: Extended lifespan of yeast by 70%

Summary: The study found that resveratrol can mimic the effects of eating less food to slow down ageing, leading to a significant increase in the lifespan of yeast. This suggests the potential benefits of resveratrol in promoting health and longevity.

Read more

Antioxidant

 Antioxidant effects of resveratrol in the cardiovascular system– Review

Outcome: Resveratrol acts as an indirect antioxidant by regulating genes, reducing ROS production, and up-regulating antioxidant enzymes.

Summary: Resveratrol appears to provide cardiovascular benefits mainly through its role as a gene regulator, decreasing ROS generation in mitochondria , rather than directly scavenging free radicals.

Read more

 Antioxidant Effects of Resveratrol in Intervertebral Disk Degeneration – Review

Outcome: Resveratrol reduces oxidative stress by scavenging free radicals and supporting mitochondrial function.

Summary: Resveratrol acts as an antioxidant by reducing reactive oxygen species, which may slow the progression of intervertebral disk degeneration.

Read more

Inflammation

The Role of Resveratrol on Rheumatoid Arthritis: From Bench to Bedside – Review

Outcome: The study assesses the potential benefits of resveratrol, a natural compound found in grapes and red wine, in treating rheumatoid arthritis (RA) by targeting inflammation and immune responses.

Summary: Resveratrol, known for its antioxidant properties, may help treat rheumatoid arthritis by reducing inflammation and protecting joints. Research suggests it could complement existing RA treatments, though more studies are needed to confirm its effectiveness and determine optimal dosages.

Read more

Effect of Resveratrol Supplementation on Inflammatory Markers – A Systematic Review and Meta-analysis of Randomised Controlled Trials

Dosage: Mixed

Outcome: Reduction in levels of TNF-α and hs-CRP, two markers of inflammation

Summary: This study found that taking resveratrol can help lower certain signs of inflammation in the body. This suggests resveratrol might be useful alongside other treatments for diseases linked to inflammation.

Read more

Everything You Need To Know About Trans Resveratrol

Resveratrol is a natural plant flavonoid found in red wine, grape skins, berries, and plants like Japanese Knotweed, a common supplement source. It is produced by plants in response to stress, injury, or pathogens as part of their defence system.

Micronised reseveratrol has been shown in one study to be up to 3.6 times more bioavailable than standard resveratrol.

Some research shows resveratrol activates sirtuins, particularly SIRT1, which supports cellular health and longevity by aiding DNA repair, metabolism, and stress response. SIRT1 also boosts mitochondrial numbers, enhancing energy output. Resveratrol is thought to boost sirtuin activity by promoting NAD+ binding to Sirtuins. It also activates AMPK, which regulates cellular energy, by simulating a low-energy state similar to fasting. AMPK activation has been shown to also activate sirtuins.

As an antioxidant, resveratrol neutralises ROS by donating electrons to them, stabilising them. It also influences the Nrf2 pathway, enabling Nrf2 to activate genes for antioxidant production, such as glutathione.

Healthy sirtuin activity supports cellular metabolism, DNA repair, and stress response, while effective antioxidant pathways limit oxidative damage, preserving cell function. Over time, sirtuin activity and antioxidant defences decline due to lower NAD levels, poor diet, stress, and exposure to toxins. Reduced sirtuin function and antioxidants weaken cellular repair and decrease overall cell protection. This decline increases oxidative stress and elevates reactive oxygen species (ROS), overwhelming the cell’s defences and causing chronic inflammation, DNA damage, and faster cellular ageing.

Around middle age (40–50 years), metabolism and cellular health decline, reducing sirtuin activity and antioxidant responses. Supporting these functions helps maintain mobility by protecting muscles and joints, promotes cognitive health by reducing neuroinflammation, and preserves cellular function, contributing to prolonged independence and resilience with age.

Consider the following statements. If any of the following statements apply to you, resveratrol could be the supplement you’re looking for:

  • I’m interested in supplements that support cellular health and longevity.
  • I’ve heard about the important role sirtuins play and I am looking for ways to better support their activity.
  • I’m concerned about oxidative stress and its impact on my health, and I want antioxidant support.
  • My longevity healthy care professional recommended resveratrol as part of my anti ageing protocol.
Made to GMP Standards
ISO 9001 Certified UK Company
Independent Testing for Purity

Transparent Testing

Every batch is independently tested for identity, potency, contaminants, heavy metals, and microbial markers.

View all product tests

Trans Resveratrol Powder test results

Date • Batch # • Results

Purity results include Heavy Metals

Current Batch:

April 2026

•

2600064

Previous results:

June 2025

•

2500226, 2401062


September 2024

•

BN2300594


May 2023

•

TRES12012023


December 2022

•

T-RES12082022

Frequently Asked Questions

Some research shows resveratrol activates sirtuins, particularly SIRT1, which supports cellular health and longevity by aiding DNA repair, metabolism, and stress response. SIRT1 also boosts mitochondrial numbers, enhancing energy output. Resveratrol is thought to boost sirtuin activity by promoting NAD+ binding to Sirtuins. It also activates AMPK, which regulates cellular energy, by simulating a low-energy state similar to fasting. AMPK activation has been shown to also activate sirtuins.

Olive oil, avocados and grass-fed dairy products such as yoghurt are examples of healthy fats you can take Resveratrol with.

Cis and trans resveratrol are two different isomers or shapes of the same resveratrol molecule. The trans form of resveratrol is more commonly found in nature and  is better absorbed by the body (higher bioavailability) and is therefore the form used in supplements.

Certainty of purity.

We are committed to the following quality controls to ensure consistency, reliability, and transparency in every product. Our goal is to raise industry standards and give you clear reasons to trust what you’re taking.
  • GMP Certified Facility

    All products are made to cGMP (current Good Manufacturing Practice) standards, the global benchmark for supplement quality. GMP standards ensure strict control over how our supplements are produced, covering everything from cleanliness to documentation and quality control. Every step is monitored to guarantee consistency and safety in every batch, so you receive the same high-quality product every time.

  • Third-Party Tested

    At the foundation of what we offer is certainty of product quality through consistent third-party testing, specifically for purity.

  • ISO Quality Managed

    ISO 9001:2015 standards are an internationally recognised framework for effective quality management. This accreditation means we follow a structured system of continuous improvement, always refining our processes to enhance product consistency and customer satisfaction. ISO accreditation ensures that every aspect of our operations, from production to customer service, is optimised. This means better oversight, reduced risk of errors, and a clear focus on delivering consistent results.

  • Transparency

    We believe you should have full clarity about what you’re putting in your body and the steps we take to ensure the quality of our supplements. That’s why we are transparent and open about every part of our process.

  • GMP Certified Facility

    Droplets

    Our supplements are manufactured in the UK, at facilities in Oxford and the North of England, following Good Manufacturing Practice (GMP) standards.

    GMP sets requirements for hygiene, production, quality control, and traceability, helping ensure supplements are consistently manufactured under controlled conditions.

    Our manufacturing partners hold independently issued GMP certificates. Rather than simply asking you to take our word for it, we've made these available below for you to review.

    Our UK Manufacturers' GMP Certificates

    Issued by Eurofins and SGS.

    Manufacturer 1

    Manufacturer 2

    Manufacturer names have been redacted for commercial confidentiality.

    Third-Party Tested

    Date • Batch # • Results

    Purity results include Heavy Metals

    Current Batch:

    April 2026

    •

    2600064

    Previous results:

    June 2025

    •

    2500226, 2401062


    September 2024

    •

    BN2300594


    May 2023

    •

    TRES12012023


    December 2022

    •

    T-RES12082022

    ISO Quality Managed

    Vitality Pro is independently certified to ISO 9001:2015, an internationally recognised standard for quality management systems.

    Maintaining this certification requires ongoing monitoring, documented checks, regular reporting and independent audits. These processes help identify areas for improvement, ensure issues are addressed, and continually strengthen the systems and controls behind our supplements. It's a commitment to quality that must be demonstrated and maintained, not simply claimed.

    We believe quality should be independently verified, not simply claimed. You can view our ISO 9001:2015 certificate below.

    Our ISO 9001:2015 Certificate

    View Our Certificate

    Transparency

    We believe you should have full clarity about what you’re putting in your body and the steps we take to ensure the quality of our supplements. That’s why we are transparent and open about every part of our process.

    Transparency means we share all the details that matter—how our products are made, tested, and verified. From publishing third-party test results to offering clear ingredient labels, we provide you with the information you need to make informed choices about your supplements. Nothing is hidden, and every product comes with full accountability.

    In a world where many supplement companies keep you in the dark, we believe you deserve complete honesty. Being transparent allows you to trust that you’re getting exactly what you expect—pure, tested supplements without hidden risks. It’s about empowering you to make confident decisions and focus on your health journey without second-guessing the products you take.

    Trusted By Professionals & Industry Experts

  • Dr. Ahmet Ozyigit

    Dr. Ahmet Ozyigit, MD, MSc, PgDip

    Head of Clinical Research at Elite Hospital

    "As a physician, purity of a product is my main concern when it comes to recommending supplements for my patients. The line of products offered by vitalityPRO is not only in line with the latest research in anti-ageing, but is also third-party tested and purity checked, which is of utmost importance for receiving maximal benefits from treatment."

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    Simon Jones, MBChB, MRCP, MSc

    Lead Academy Doctor at a Premier League Football Club

    "Vitality Pro is a fantastic company, clearly striving to achieve the highest standard and reliability of supplements on the market. Their range really is at the cutting edge of longevity supplements, and the independent third-party testing is incredibly reassuring in terms of quality."

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    Casey Vincent, Two-Time Olympian

    Australian Olympics Sprinter 2000-2004

    “I have done my research on vitalityPRO products and without a doubt have found their supplements to be far superior to the competition”

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    Tony Pemberton, FdENG

    Certified Epigenetic Coach

    "I'm very discerning of either overpriced supplements or poor quality ingredients, but I have to say Vitality PRO products are superb while still being great value. I use them myself for improving ageing biomarkers, and I am happy to recommend them to both my clients and viewership."

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    Kim Forteza, MSc, PGCert, TPU, CNS

    Elite Athlete Coach

    "I have found Vitality Pro to have a great commitment to the client. They generate trust due to their service, presentation, formulation, technical explanations, and third-party analysis of each of their products. It is a brand that I always recommend when looking for excellence in a product, both for my athletes and for all people looking for supplementation with guarantees."

  • Emel Gunay

    Emel Gunay, DipCNM, mBANT, mIFM

    Nutritional Therapist and Research Manager at OMNOS

    "V​itality-PRO offers excellent customer support, knowledgeable staff, and great value for money on high-quality supplements. ​​The products are of outstanding quality, and I appreciate their dedication to quality and transparency, which ensures safety and compliance for my clients. I​ can highly recommend ​them."

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    Jonny Hirtenstein, MChiro, DC, ACN

    Founder and Lead Chiropractor at Foundation For Life

    ”As a clinician I appreciate Vitality Pro's passion for producing products that are designed to deliver great results and knowing that they independently test all the batches of the products is very reassuring. Ultimately I know that they care about everything they do, and are striving to produce some of the most cutting edge products on the market.”

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    Dr. Zain Khan, MBBS

    British Medical Association Executive Council Member

    “A professional supplement company who aim to be transparent, innovative and trustworthy. They invest time and money into conducting independent lab tests to verify the purity and quality of their products, ensuring that you receive precisely what you pay for.”

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    Specialise in being a doctor

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    Andy Smith, PEMF Expert

    CEO of NewMed & Founder of CELLER8

    "Vitality Pro offers an impressive range of high-quality supplements, and their Magnesium Glycinate is my personal favourite. I love stacking it with my daily PEMF sessions as they complement each other perfectly for enhanced wellness. I trust Vitality Pro for reliable vitamins and supplements, and I’m always happy to recommend them to my customers!"

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    We want you to feel confident trying our products. If you're not satisfied for any reason, you can return your product within 60 days of receiving it for a full refund.

    This includes if you've changed your mind, haven't noticed the difference you hoped for, experienced side effects, or simply decided the product isn't right for you.

    How to claim the guarantee

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    The 60-Day Satisfaction Guarantee does not apply to our 100g NMN or 100g Resveratrol products, as we offer smaller 20g and 30g options to give you the opportunity to try the product before committing to a larger supply.

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