Vitality Pro
Vitality Pro
Cellular Health Longevity Antioxidant

Trans Resveratrol Powder

Sirtuin Activator
  • Trans Resveratrol Powder
  • Trans Resveratrol Powder
  • Trans Resveratrol Powder
  • Trans Resveratrol Powder
  • Trans Resveratrol Powder
  • Trans Resveratrol Powder
    • Trans Resveratrol Powder
    Trans Resveratrol Powder
    Trans Resveratrol Powder
    Trans Resveratrol Powder
    Trans Resveratrol Powder
    Trans Resveratrol Powder

    Third-Party Tested

    GMP Certified Facility

    ISO Quality Managed

    • Why Others Choose Vitality Pro?

    Trans Resveratrol Powder

    Sirtuin Activator

    Trans-Resveratrol, in micronised powder form, is an antioxidant also believed to activate sirtuin genes responsible for activities most linked to longevity, such as DNA repair, metabolism, and stress response.

    Features

    • 500mg per scoop
    • Take 1-2 scoops per day (scoop included)
    • Formulated with micronised Resveratrol, known for its superior bioavailability
    • Suitable for vegans 
    • Free from common allergens

    Quantity

    The longer you subscribe, the more you save.

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    • 5% off first 3 renewals
    • 10% off renewals 4-8
    • 15% off from renewal 9+

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    Third-Party Tested

    Date • Batch # • Results

    Purity results include Heavy Metals

    Current Batch:

    April 2026

    •

    2600064

    100.1% Purity and Microbiology

    Previous results:

    June 2025

    •

    2500226, 2401062

    100% Purity and Microbiology

    September 2024

    •

    BN2300594

    99.8% Purity and Microbiology

    May 2023

    •

    TRES12012023

    99% Purity

    December 2022

    •

    T-RES12082022

    98% Purity

    GMP Certified Facility

    Our supplements are manufactured in the UK, at facilities in Oxford and the North of England, following Good Manufacturing Practice (GMP) standards.

    GMP sets requirements for hygiene, production, quality control, and traceability, helping ensure supplements are consistently manufactured under controlled conditions.

    Our manufacturing partners hold independently issued GMP certificates. Rather than simply asking you to take our word for it, we've made these available below for you to review.

    Our UK Manufacturers' GMP Certificates

    Issued by Eurofins and SGS.

    Manufacturer 1

    Manufacturer 2

    Manufacturer names have been redacted for commercial confidentiality.

    ISO Quality Managed

    Vitality Pro is independently certified to ISO 9001:2015, an internationally recognised standard for quality management systems.

    Maintaining this certification requires ongoing monitoring, documented checks, regular reporting and independent audits. These processes help identify areas for improvement, ensure issues are addressed, and continually strengthen the systems and controls behind our supplements. It's a commitment to quality that must be demonstrated and maintained, not simply claimed.

    We believe quality should be independently verified, not simply claimed. You can view our ISO 9001:2015 certificate below.

    Our ISO 9001:2015 Certificate

    View Our Certificate

    Recommended Use

    Take either 1 or 2 scoops per day in the morning with a healthy, high-fat meal. This is equal to either 500mg or 1000mg of Trans-Resveratrol.

    Trans-Resveratrol is fat-soluble, meaning it is best absorbed by the body when taken with a fat source. Healthy options for this include avocado, yoghurt, coconut or extra virgin olive oil.

    Ingredients

    View supplement label

    Servings Per Container: 60 (30g) or 200 (100g)

    Amount Per Serving Amount %NRV
    Trans-Resveratrol 500mg *
    Micronised from Japanese Knotweed, natural

    Nutrient Reference Value not established*

    Other ingredients: None

    Suitable for vegans. Contains no fillers, GMOs, common allergens, artificial colours, preservatives or flavours.

    Storage & Stability

    To maintain the potency and quality of your Resveratrol supplements, store them in a cool (20°C-25°C), dry place, and away from light. Trans-Resveratrol must not be exposed to light for long periods as it will degrade to Cis-Resveratrol. Please store your Resveratrol in a dark environment.

    Quality Standards

    Manufacturing: All products are made to GMP standards and have been quality-managed in accordance with the UK standard ISO 9001:2015. Third-party tested: To ensure the highest purity and maximum effectiveness, each new batch of products undergoes third-party testing by ISO 17025 accreditated Micro Quality Labs. You can view all testing certificates at www.vitality-pro.com/batch-testing.

    Safety & Warnings

    Do not exceed the recommended daily dose. Food supplements should not replace a varied and balanced diet and a healthy lifestyle. If you are pregnant, breastfeeding, under 18 or taking any medication, consult a doctor before use. Stop use if adverse reactions occur.

    Interactions: Resveratrol is known to inhibit members of the Cytochrome P450 class of enzymes. As a result, it may interfere with antiplatelet and anticoagulant medications such as Warfarin. Additionally, resveratrol is classed as a phytoestrogen, a plant molecule that can mimic the effects of oestrogen in the body. Therefore, individuals who are hormone replacement therapies should therefore consult with their doctors before adding resveratrol to their longevity protocols. If you are taking these medications or any other medication, please first speak with your doctor before adding Resveratrol to your supplement regime.

    For further information regarding any other potential drug and supplement interactions of Resveratrol please see the ingredient profile on Drug Bank.* Allergy: This product does not contain any common allergens; however, it should not be used by anyone with a history of hypersensitivity to its ingredients or those taking medications that may interact with it.

    Pregnancy: If pregnant, consult your health professional before using this product.

    *Drug Bank is an independent website that lists potential interactions between the ingredients in Trans-Resvertrol and other medications and supplements. It may not, however, list all known possible interactions. If you are on any medications or supplements you feel may interact negatively with Trans-Resvertrol please first speak with your doctor before using this product.
    1

    Key Studies to Consider

    While individual results may vary due to personal health conditions, genetics, and lifestyle choices, we guarantee that the supplements you receive are made with ingredients of the highest purity, similar to those used in scientific studies, to ensure maximum results.

    Sirtuin Activator

    *The below research, carried out by Dr David Sinclair and others, suggests that Resveratrol may enhance the activity of SIRT1 through several mechanisms, such as mimicking the effects of caloric restriction. The pathways and the extent of how effectively Resveratrol can activate SIRT1 remain a topic of ongoing investigation.

     Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan – Cell Study

    Dosage: Not specified

    Outcome: Increased lifespan and DNA stability in yeast

    Summary: Resveratrol, which boosts NAD+ and activates sirtuins, extended the lifespan of yeast cells by 70%, similar to the effects of calorie restriction. This suggests that NAD+ and sirtuin activation could promote longevity.

    Read more

     The Role and Mechanism of SIRT1 in Resveratrol-regulated Osteoblast Autophagy in Osteoporosis Rats – Animal study

    Dosage: 5 mg/kg/day and 45 mg/kg/day resveratrol for 8 weeks

    Outcome: Resveratrol improved bone density and promoted autophagy in bone cells through SIRT1 activation.

    Summary: High-dose resveratrol activated SIRT1 and enhanced mitophagy in osteoblasts, protecting against bone loss in osteoporosis rats.

    Read more

    Longevity

    *Sirtuin 1 is a molecule that when activated has been shown to increase lifespan in both cell and mouse studies. While Resveratrol is believed to work by activating this molecule there is still debate in the longevity community about its efficacy of this.

    Resveratrol Improves Health and Survival of Mice on a High-Calorie Diet – Preclinical Animal Study

    Dosage: Resveratrol (dosage not specified)

    Outcome: Increased lifespan and improved health markers in mice fed a high-calorie diet

    Summary: In middle-aged mice, resveratrol improved general health and increased lifespan, mimicking the benefits of a standard diet. This was noted through several markers including better insulin sensitivity, lower levels of certain ageing-related factors, more mitochondria (energy-producing structures in cells) and enhanced physical ability.

    Read more

    Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan – Cell Study

    Dosage: Resveratrol, a compound found in red wine

    Outcome: Extended lifespan of yeast by 70%

    Summary: The study found that resveratrol can mimic the effects of eating less food to slow down ageing, leading to a significant increase in the lifespan of yeast. This suggests the potential benefits of resveratrol in promoting health and longevity.

    Read more

    Antioxidant

     Antioxidant effects of resveratrol in the cardiovascular system– Review

    Outcome: Resveratrol acts as an indirect antioxidant by regulating genes, reducing ROS production, and up-regulating antioxidant enzymes.

    Summary: Resveratrol appears to provide cardiovascular benefits mainly through its role as a gene regulator, decreasing ROS generation in mitochondria , rather than directly scavenging free radicals.

    Read more

     Antioxidant Effects of Resveratrol in Intervertebral Disk Degeneration – Review

    Outcome: Resveratrol reduces oxidative stress by scavenging free radicals and supporting mitochondrial function.

    Summary: Resveratrol acts as an antioxidant by reducing reactive oxygen species, which may slow the progression of intervertebral disk degeneration.

    Read more

    Inflammation

    The Role of Resveratrol on Rheumatoid Arthritis: From Bench to Bedside – Review

    Outcome: The study assesses the potential benefits of resveratrol, a natural compound found in grapes and red wine, in treating rheumatoid arthritis (RA) by targeting inflammation and immune responses.

    Summary: Resveratrol, known for its antioxidant properties, may help treat rheumatoid arthritis by reducing inflammation and protecting joints. Research suggests it could complement existing RA treatments, though more studies are needed to confirm its effectiveness and determine optimal dosages.

    Read more

    Effect of Resveratrol Supplementation on Inflammatory Markers – A Systematic Review and Meta-analysis of Randomised Controlled Trials

    Dosage: Mixed

    Outcome: Reduction in levels of TNF-α and hs-CRP, two markers of inflammation

    Summary: This study found that taking resveratrol can help lower certain signs of inflammation in the body. This suggests resveratrol might be useful alongside other treatments for diseases linked to inflammation.

    Read more

    Everything You Need To Know About TMG

    Trimethylglycine (TMG), also known as betaine, is a derivative of the amino acid glycine. It is found naturally in the body and in certain foods, such as beetroot, spinach, and whole grains. TMG supports methylation, a biochemical process essential for cellular function and adaptation to the body’s changing demands.

    TMG supports methylation by converting excess homocysteine into methionine. Through this process, TMG attaches a methyl group to homocysteine, forming methionine, which is then used to produce S-adenosylmethionine (SAMe), a key methyl donor which supports methylation by ensuring there are enough “methyl groups” to meet the body’s methylation demands.

    Methylation modifies DNA by adding methyl groups to specific molecules in the body, turning certain genes on or off, and ensuring essential functions like repair and growth are active while silencing unnecessary processes for cell stability. In detoxification, methylation transforms toxins into safer, water-soluble compounds that the liver can then expel from the body. For neurotransmitter production, SAMe donates methyl groups to create serotonin and dopamine building blocks, thereby aiding in their formation. Additionally, by donating methyl groups to creatine precursors, methylation helps to increase creatine availability, supporting energy demands during high-intensity exercise.

    Long-term NMN or NR use can deplete methyl groups because excess nicotinamide produced in the NMN-to-NAD cycle requires methylation for removal. This depletion might lead to fatigue in some individuals. TMG can help replenish these methyl groups, though it’s not necessary for everyone. If you experience fatigue with NMN or NR, it is recommended that you consider supplementing with TMG.

    Healthy methylation supports essential bodily functions by adding or removing chemical groups (methyl groups) to activate or silence genes as needed. This is required for cell growth, repair, and the regulation of cellular functions. In a simple sense, methyl groups can be considered the fuel for methylation.

    It is estimated that up to 70% of the population has a variant in the MTHFR gene, known as a polymorphism. The majority of these variants can lead to reduced methylation as they affect an enzyme essential for producing SAMe – the body’s primary methyl donor. Consult a healthcare professional if you have concerns about your MTHFR status.

    Research suggests that methylation capacity declines with age, leading to impaired cellular function, inefficient detoxification, and increased homocysteine levels, all of which are linked to age-related decline. Supporting optimal methylation activity and keeping homocysteine levels within a healthy range may help support long-term cellular health.

    Consider the statements below. If you find one or more relatable, TMG might be the supplement you’re looking for:

    • I wish to support a healthy cardiovascular system by managing homocysteine levels.
    • I take NAD precursors and fatigue is a constant battle for me. I seek to improve my energy levels for a more active lifestyle.
    • My healthcare provider mentioned the importance of supporting methylation processes for overall health.
    • I’m interested in supporting a healthy mood balance and I feel my methylation status is having an impact.
    • I have a reduction in MTHFR activity and wish to support healthy methylation.
    Made to GMP Standards
    ISO 9001 Certified UK Company
    Independent Testing for Purity

    Transparent Testing

    Every batch is independently tested for identity, potency, contaminants, heavy metals, and microbial markers.

    View all product tests

    Trans Resveratrol Powder test results

    Date • Batch # • Results

    Purity results include Heavy Metals

    Current Batch:

    April 2026

    •

    2600064

    100.1% Purity and Microbiology

    Previous results:

    June 2025

    •

    2500226, 2401062

    100% Purity and Microbiology

    September 2024

    •

    BN2300594

    99.8% Purity and Microbiology

    May 2023

    •

    TRES12012023

    99% Purity

    December 2022

    •

    T-RES12082022

    98% Purity

    Frequently Asked Questions

    This TMG supplement is Betaine Anhydrous and will not raise stomach acid.

    Yes, TMG is made in the body.

    TMG is naturally found in foods such as beets, broccoli, shellfish, and spinach. However, due to the low amounts present in food, a supplement is likely the best option to receive the full benefits of TMG.

    TMG supports methylation in the body. For some, TMG supplementation can lead to excess methylation, which can result in symptoms such as anxiety and fatigue. If you experience any of these symptoms, it is recommended that you stop taking TMG.

    Certainty of purity.

    We are committed to the following quality controls to ensure consistency, reliability, and transparency in every product. Our goal is to raise industry standards and give you clear reasons to trust what you’re taking.

  • GMP Certified Facility

    All products are made to cGMP (current Good Manufacturing Practice) standards, the global benchmark for supplement quality. GMP standards ensure strict control over how our supplements are produced, covering everything from cleanliness to documentation and quality control. Every step is monitored to guarantee consistency and safety in every batch, so you receive the same high-quality product every time.

  • Third-Party Tested

    At the foundation of what we offer is certainty of product quality through consistent third-party testing, specifically for purity.

  • ISO Quality Managed

    ISO 9001:2015 standards are an internationally recognised framework for effective quality management. This accreditation means we follow a structured system of continuous improvement, always refining our processes to enhance product consistency and customer satisfaction. ISO accreditation ensures that every aspect of our operations, from production to customer service, is optimised. This means better oversight, reduced risk of errors, and a clear focus on delivering consistent results.

  • Transparency

    We believe you should have full clarity about what you’re putting in your body and the steps we take to ensure the quality of our supplements. That’s why we are transparent and open about every part of our process.

    •

    GMP Certified Facility

    Droplets

    Our supplements are manufactured in the UK, at facilities in Oxford and the North of England, following Good Manufacturing Practice (GMP) standards.

    GMP sets requirements for hygiene, production, quality control, and traceability, helping ensure supplements are consistently manufactured under controlled conditions.

    Our manufacturing partners hold independently issued GMP certificates. Rather than simply asking you to take our word for it, we've made these available below for you to review.

    Our UK Manufacturers' GMP Certificates

    Issued by Eurofins and SGS.

    Manufacturer 1

    Manufacturer 2

    Manufacturer names have been redacted for commercial confidentiality.

    Third-Party Tested

    Date • Batch # • Results

    Purity results include Heavy Metals

    Current Batch:

    April 2026

    •

    2600064

    100.1% Purity and Microbiology

    Previous results:

    June 2025

    •

    2500226, 2401062

    100% Purity and Microbiology

    September 2024

    •

    BN2300594

    99.8% Purity and Microbiology

    May 2023

    •

    TRES12012023

    99% Purity

    December 2022

    •

    T-RES12082022

    98% Purity

    ISO Quality Managed

    Vitality Pro is independently certified to ISO 9001:2015, an internationally recognised standard for quality management systems.

    Maintaining this certification requires ongoing monitoring, documented checks, regular reporting and independent audits. These processes help identify areas for improvement, ensure issues are addressed, and continually strengthen the systems and controls behind our supplements. It's a commitment to quality that must be demonstrated and maintained, not simply claimed.

    We believe quality should be independently verified, not simply claimed. You can view our ISO 9001:2015 certificate below.

    Our ISO 9001:2015 Certificate

    View Our Certificate

    Transparency

    We believe you should have full clarity about what you’re putting in your body and the steps we take to ensure the quality of our supplements. That’s why we are transparent and open about every part of our process.

    Transparency means we share all the details that matter—how our products are made, tested, and verified. From publishing third-party test results to offering clear ingredient labels, we provide you with the information you need to make informed choices about your supplements. Nothing is hidden, and every product comes with full accountability.

    In a world where many supplement companies keep you in the dark, we believe you deserve complete honesty. Being transparent allows you to trust that you’re getting exactly what you expect—pure, tested supplements without hidden risks. It’s about empowering you to make confident decisions and focus on your health journey without second-guessing the products you take.

    Trusted By Professionals & Industry Experts

  • Dr. Ahmet Ozyigit

    Dr. Ahmet Ozyigit, MD, MSc, PgDip

    Head of Clinical Research at Elite Hospital

    "As a physician, purity of a product is my main concern when it comes to recommending supplements for my patients. The line of products offered by vitalityPRO is not only in line with the latest research in anti-ageing, but is also third-party tested and purity checked, which is of utmost importance for receiving maximal benefits from treatment."

  • Simon Jones

    Simon Jones, MBChB, MRCP, MSc

    Lead Academy Doctor at a Premier League Football Club

    "Vitality Pro is a fantastic company, clearly striving to achieve the highest standard and reliability of supplements on the market. Their range really is at the cutting edge of longevity supplements, and the independent third-party testing is incredibly reassuring in terms of quality."

  • Casey Vincent

    Casey Vincent, Two-Time Olympian

    Australian Olympics Sprinter 2000-2004

    “I have done my research on vitalityPRO products and without a doubt have found their supplements to be far superior to the competition”

  • Tony Pemberton

    Tony Pemberton, FdENG

    Certified Epigenetic Coach

    "I'm very discerning of either overpriced supplements or poor quality ingredients, but I have to say Vitality PRO products are superb while still being great value. I use them myself for improving ageing biomarkers, and I am happy to recommend them to both my clients and viewership."

  • Kim Forteza

    Kim Forteza, MSc, PGCert, TPU, CNS

    Elite Athlete Coach

    "I have found Vitality Pro to have a great commitment to the client. They generate trust due to their service, presentation, formulation, technical explanations, and third-party analysis of each of their products. It is a brand that I always recommend when looking for excellence in a product, both for my athletes and for all people looking for supplementation with guarantees."

  • Emel Gunay

    Emel Gunay, DipCNM, mBANT, mIFM

    Nutritional Therapist and Research Manager at OMNOS

    "V​itality-PRO offers excellent customer support, knowledgeable staff, and great value for money on high-quality supplements. ​​The products are of outstanding quality, and I appreciate their dedication to quality and transparency, which ensures safety and compliance for my clients. I​ can highly recommend ​them."

  • Jonny Hirtenstein

    Jonny Hirtenstein, MChiro, DC, ACN

    Founder and Lead Chiropractor at Foundation For Life

    ”As a clinician I appreciate Vitality Pro's passion for producing products that are designed to deliver great results and knowing that they independently test all the batches of the products is very reassuring. Ultimately I know that they care about everything they do, and are striving to produce some of the most cutting edge products on the market.”

  • Dr. Zain Khan

    Dr. Zain Khan, MBBS

    British Medical Association Executive Council Member

    “A professional supplement company who aim to be transparent, innovative and trustworthy. They invest time and money into conducting independent lab tests to verify the purity and quality of their products, ensuring that you receive precisely what you pay for.”

  • Dr James Hetfield

    Dr James Hetfield, Lead Doctor

    Lead Doctor

    Specialise in being a doctor

  • Andy Smith

    Andy Smith, PEMF Expert

    CEO of NewMed & Founder of CELLER8

    "Vitality Pro offers an impressive range of high-quality supplements, and their Magnesium Glycinate is my personal favourite. I love stacking it with my daily PEMF sessions as they complement each other perfectly for enhanced wellness. I trust Vitality Pro for reliable vitamins and supplements, and I’m always happy to recommend them to my customers!"

    •

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    Customs Fees: There may be customs to pay depending on your country’s local requirements. We will do what we can to avoid or minimise these as much as possible. If import charges are required, you will receive an email or text with customs clearance and payment instructions.

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    Money Back Guarantee

    60 Day Satisfaction Guarantee

    We want you to feel confident trying our products. If you're not satisfied for any reason, you can return your product within 60 days of receiving it for a full refund.

    This includes if you've changed your mind, haven't noticed the difference you hoped for, experienced side effects, or simply decided the product isn't right for you.

    How to claim the guarantee

    • Email returns@vitality-pro.com with your order number, which you'll find in your order confirmation email.
    • We'll send you the address to return your product to. Please include a note with your order number inside the parcel so we can identify your return.
    • Once your return is received, we'll process your refund within 7 days.

    Return shipping costs: You'll need to arrange and pay for return shipping unless the product arrived faulty or damaged. All returns are sent to our UK return address. If you're ordering from outside the UK, please keep in mind that international return shipping can be expensive.

    Multiple bottles or larger quantities: If you buy multiple bottles or a larger quantity of the same product in a single order, the guarantee covers the use of one bottle, or the smallest individual size supplied. Any additional unopened units must be returned to receive a refund.

    For example, if you order 180 capsules and receive 2 × 90-capsule bottles, you can open and use one 90-capsule bottle. The second bottle must be returned.

    The 60-Day Satisfaction Guarantee does not apply to our 100g NMN or 100g Resveratrol products, as we offer smaller 20g and 30g options to give you the opportunity to try the product before committing to a larger supply.

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