Vitality Pro
Vitality Pro
Antioxidant Longevity Cellular Health

Pterostilbene Advanced

Sirtuin Activator
  • Pterostilbene Advanced
  • Pterostilbene Advanced
  • Pterostilbene Advanced
  • Pterostilbene Advanced
  • Pterostilbene Advanced
    • Pterostilbene Advanced
    Pterostilbene Advanced
    Pterostilbene Advanced
    Pterostilbene Advanced
    Pterostilbene Advanced

    Third-Party Tested

    GMP Certified Facility

    ISO Quality Managed

    • Why Others Choose Vitality Pro?

    Pterostilbene Advanced

    Sirtuin Activator

    Pterostilbene is a natural plant molecule found in blueberries. It is similar to Resveratrol but is thought to be up to 4x more bioavailable due to its unique molecular structure.

    Features

    • 100mg per capsule
    • Take 1-2 per day
    • Contains additional Piperine to support absorption and Grapeseed Extract to protect heart health
    • Suitable for vegans 
    • Free from common allergens

    Quantity

    The longer you subscribe, the more you save.

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    • 5% off first 3 renewals
    • 10% off renewals 4-8
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    Third-Party Tested

    Date • Batch # • Results

    Purity results include Heavy Metals

    Current Batch:

    January 2026

    •

    2501436

    99.5% Purity and Microbiology

    Previous results:

    May 2025

    •

    PB250104 – 2500222

    98.4% Purity and Microbiology

    August 2024

    •

    BN-PB231203

    100% Purity and Microbiology

    December 2023

    •

    PTERO12042023

    99.6% Purity and Microbiology

    April 2023

    •

    PTERO20221101

    98% Purity

    October 2022

    •

    PTERO10202022

    100% Purity

    March 2022

    •

    PTERO03172022

    98% Purity

    March 2021

    •

    PTERO03042021

    98.3% Purity

    December 2019

    •

    PTERO11252019

    99.2% Purity

    GMP Certified Facility

    Our supplements are manufactured in the UK, at facilities in Oxford and the North of England, following Good Manufacturing Practice (GMP) standards.

    GMP sets requirements for hygiene, production, quality control, and traceability, helping ensure supplements are consistently manufactured under controlled conditions.

    Our manufacturing partners hold independently issued GMP certificates. Rather than simply asking you to take our word for it, we've made these available below for you to review.

    Our UK Manufacturers' GMP Certificates

    Issued by Eurofins and SGS.

    Manufacturer 1

    Manufacturer 2

    Manufacturer names have been redacted for commercial confidentiality.

    ISO Quality Managed

    Vitality Pro is independently certified to ISO 9001:2015, an internationally recognised standard for quality management systems.

    Maintaining this certification requires ongoing monitoring, documented checks, regular reporting and independent audits. These processes help identify areas for improvement, ensure issues are addressed, and continually strengthen the systems and controls behind our supplements. It's a commitment to quality that must be demonstrated and maintained, not simply claimed.

    We believe quality should be independently verified, not simply claimed. You can view our ISO 9001:2015 certificate below.

    Our ISO 9001:2015 Certificate

    View Our Certificate

    Recommended Use

    For antioxidant support, take one capsule of Advanced Pterostilbene daily. To support longevity and upregulate Sirtuin activity, increase the dose to two capsules daily.

    Pterostilbene can be taken at any time throughout the day. However, if you are taking Pterostilbene with NAD boosters, we recommend taking them together in the morning.

    Pterostilbene is fat-soluble, meaning it is better absorbed by the body when taken with a fat source. This can be a meal or a healthy snack, such as avocado, yoghurt, coconut, or extra virgin olive oil.

    Since Pterostilbene is an antioxidant, it may blunt some of the positive effects of weight training exercise. Therefore, we recommend not taking it around resistance training sessions.

    Ingredients

    View supplement label

    Capsules Per Container: 60

    Amount Per Capsule Amount %NRV
    Trans-Pterostilbene 100mg *
    Grapeseed Extract 200mg *
    Piperine 10mg *

    Nutrient Reference Value not established*

    Other ingredients (all natural): Microcrystalline Cellulose (MCC), Vegetable Cellulose Capsule (HPMC)

    Suitable for vegans. Contains no GMOs, common allergens, artificial colours, preservatives or flavours.

    Storage & Stability

    To maintain the potency and quality of your Pterostilbene supplements, store them in a cool (20°C-25°C), dry place away from light.

    Quality Standards

    Manufacturing: All products are made to GMP standards and have been quality-managed in accordance with the UK standard ISO 9001:2015. Third-party tested: To ensure the highest purity and maximum effectiveness, each new batch of products undergoes third-party testing by ISO 17025 accreditated Micro Quality Labs. You can view all testing certificates at www.vitality-pro.com/batch-testing.

    Safety & Warnings

    Do not exceed the recommended daily dose. Food supplements should not replace a varied and balanced diet and a healthy lifestyle. If you are pregnant, breastfeeding, under 18 or taking any medication, consult a doctor before use. Stop use if adverse reactions occur.

    Interactions: Pterostilbene is known to inhibit members of the Cytochrome P450 class of enzymes. As a result, it may interfere with antiplatelet and blood-thinning medications such as Warfarin. Pterostilbene has also been shown to interact with certain SSRI medications including Sertraline. If you are taking this medication or any other medications, please speak with your doctor before adding Pterostilbene to your supplement regime.

    For further information regarding any other potential drug and supplement interactions of Pterostilbene please see the ingredient profile on Drug Bank using the link below.* Allergy: This product does not contain any common allergens; however, it should not be used by anyone with a history of hypersensitivity to its ingredients or those taking medications that may interact with it.

    Pregnancy: If pregnant, consult your health professional before using this product.

    *Drug Bank is an independent website that lists potential interactions between the ingredients in Advanced Pterostilbene and other medications and supplements. It may not, however, list all known possible interactions. If you are on any medications or supplements you feel may interact negatively with Advanced Pterostilbene please first speak with your doctor before using this product.
    1

    Key Studies to Consider

    While individual results may vary due to personal health conditions, genetics, and lifestyle choices, we guarantee that the supplements you receive are made with ingredients of the highest purity, similar to those used in scientific studies, to ensure maximum results.

    Sirtuin Activator

    Therapeutic Potential of Natural Molecules Against Alzheimer’s Disease via SIRT1 Modulation – Review

    Outcome: Potential for natural molecules to combat Alzheimer’s disease by modulating SIRT1 and associated signalling pathways

    Summary: This study highlights the role of natural molecules like pterostilbene and resveratrol in potentially treating Alzheimer’s disease. These molecules may help fight the disease by affecting SIRT1, a protein involved in brain health and longevity.

    Read more

    Antioxidant

    The Neuroprotective Effect of Pterostilbene on Oxaliplatin-Induced Peripheral Neuropathy via Its Anti-Inflammatory, Anti-Oxidative, and Anti-Apoptotic Effects: Comparative Study with Celecoxib – Comparative Study

    Dosage: Pterostilbene (40 mg/kg/day, orally for 5 weeks) and Celecoxib (30 mg/kg/day, orally for 5 weeks).

    Outcome: Improvement in nerve damage symptoms, reduction in inflammation, oxidative stress and cell death in rats

    Summary: The study found that pterostilbene and celecoxib, a drug, both helped reduce nerve damage and pain caused by oxaliplatin, a cancer treatment drug. Taking these substances alone or together helped by lowering inflammation, and oxidative stress.

    Read more

    A Review of Pterostilbene Antioxidant Activity and Disease Modification – Review

    Outcome: Antioxidant activity and disease-modifying effects of pterostilbene across multiple diseases.

    Summary: This review highlights the antioxidant and anticancer effects of pterostilbene, a compound found in blueberries, in various diseases like breast cancer, cardiovascular disease, and diabetes. The studies suggest that pterostilbene can reduce cancer cell growth, improve cardiovascular health, and manage diabetes by modulating oxidative stress and enhancing antioxidant activity. However, more research is needed to confirm these effects in humans.

    Read more

    Longevity

    Pterostilbene Promotes Mean Lifespan in Both Male and Female Drosophila Melanogaster Modulating Different Proteins in the Two Sexes – Cell Study

    Dosage: 50 and 100 micro-molar concentrations

    Outcome: Increased average lifespan in both male and female Drosophila melanogaster, with a greater effect observed in females.

    Summary: Pterostilbene extended the lifespan of both male and female flies through different mechanisms, affecting specific proteins differently in each sex. This suggests the importance of studying nutraceutical effects separately in males and females.

    Read more

    Inflammation

    Nicotinamide Riboside and Pterostilbene Reduce Liver Inflammation in NAFLD: A Clinical Trial – Randomised Double-blind Placebo-controlled Clinical Trial

    Dosage: Daily supplementation of nicotinamide riboside and pterostilbene (NRPT)

    Outcome: Reduction in liver enzyme levels as markers of hepatic inflammation

    Summary: NRPT supplementation, at the recommended dose, showed promising results in lowering liver inflammation markers, specifically reducing levels of liver enzymes ALT and GGT, and toxic lipids in patients with NAFLD.

    Read more

    Selective COX-2 Inhibitory Activity of Pterocarpus Marsupium Extract and Its Effect on PGE2 Production in Human Volunteers – Experimental Study

    Dosage: 450 mg Pterostilbene extract daily

    Outcome: Helped to control PGE2 (a molecule that helps to regulate inflammation) production in humans

    Summary: A study investigated Pterostilbene’s ability to reduce inflammation markers in blood cells and its safety in humans. It found that the extract can reduce certain inflammation markers in test conditions but did not have the same effect when tested in people. However, it was safe to use, suggesting further research is needed to find the right dose for potential benefits in treating inflammation or pain.

    Read more

    Everything You Need To Know About Pterostilbene

    Pterostilbene is a flavonoid, a type of plant compound, and an antioxidant found in blueberries, grapes, and dragon fruit. Due to its molecular structure, pterostilbene is believed to be up to 4x more bioavailable than resveratrol. Being more lipophilic (fat-attracting), pterostilbene crosses cell membranes more easily and resists rapid metabolism by the liver.

    Advanced Pterostilbene includes grapeseed extract to counteract potential increases in LDL cholesterol, a known side effect. A small dose of piperine was also added to enhance pterostilbene absorption.

    Sirtuins are proteins linked to longevity through regulating DNA repair, stress resilience, and metabolism. Sirtuin 1 (SIRT1) supports cellular energy production by promoting the creation of new mitochondria—the cell’s powerhouses. Pterostilbene is thought to activate SIRT1 by increasing levels of the energy-sensing enzyme AMPK, mimicking a low-energy state in the body that triggers SIRT1 as a survival response.

    Some debated research from Dr. David Sinclair’s lab suggests that Resveratrol may directly bind to and activate SIRT1, enhancing its ability to bind to and use NAD for energy. Due to structural similarities, we believe this is worth noting but the extent of this is still being investigated.

    Antioxidants protect cells from oxidative stress caused by reactive oxygen species (ROS). Pterostilbene functions as both a direct and indirect antioxidant: it directly stabilises ROS by donating electrons to neutralise them and indirectly boosts the body’s antioxidant defence by mimicking oxidative stress. This process activates the NRF2 enzyme, which increasing the production of the body’s own antioxidants such as Glutathione.

    Optimal sirtuin activity supports DNA repair and helps cells maintain stability under stress, which is essential for cellular longevity. A poor diet, sedentary lifestyle, chronic stress, ageing, and poor sleep all impair sirtuin activation and increase oxidative stress. Supporting sirtuin activation and antioxidant effects protects against oxidative stress and reduces cellular damage.

    Ageing is the gradual accumulation of cellular damage, leading to reduced cellular function and increased demand for the body’s resources to combat these issues. Sirtuins and antioxidants contribute to DNA repair and cellular protection by reducing oxidative stress and damage, thereby slowing cellular decline. As a result, reduced inflammation, improved stress resistance, maintained metabolism, and preserved cellular integrity, are essential for promoting longevity.

    Advanced Pterostilbene is designed to support antioxidant levels and sirtuin activation for improved cellular repair and protection.

    Consider the following statements. If you find one or more relatable, Pterostilbene might be the support you’ve been searching for:

    • I’m looking to support my body’s natural defence mechanisms against oxidative stress and inflammation.
    • After exposure to environmental pollutants or stress, I’d like to support my body’s ability to recover and maintain balance.
    • I’m already using supplements for NAD production and am interested in adding a potential SIRT1 activator to my regimen.
    • Understanding the importance of antioxidants, I’m looking to elevate my body’s ability to combat free radicals and support cellular health
    • I have tried Resveratrol but it doesn’t agree with me and I am looking for an alternative
    • My health professional recommended this supplement.
    Made to GMP Standards
    ISO 9001 Certified UK Company
    Independent Testing for Purity

    Transparent Testing

    Every batch is independently tested for identity, potency, contaminants, heavy metals, and microbial markers.

    View all product tests

    Pterostilbene Advanced test results

    Date • Batch # • Results

    Purity results include Heavy Metals

    Current Batch:

    January 2026

    •

    2501436

    99.5% Purity and Microbiology

    Previous results:

    May 2025

    •

    PB250104 – 2500222

    98.4% Purity and Microbiology

    August 2024

    •

    BN-PB231203

    100% Purity and Microbiology

    December 2023

    •

    PTERO12042023

    99.6% Purity and Microbiology

    April 2023

    •

    PTERO20221101

    98% Purity

    October 2022

    •

    PTERO10202022

    100% Purity

    March 2022

    •

    PTERO03172022

    98% Purity

    March 2021

    •

    PTERO03042021

    98.3% Purity

    December 2019

    •

    PTERO11252019

    99.2% Purity

    Frequently Asked Questions

    Some studies have shown that pterostilbene supplementation may increase LDL cholesterol; however, this study indicates that this effect can be counteracted by supplementing with grape seed extract. For this purpose, we’ve included grape seed extract in the Advanced Pterostilbene formula at a comparable dosage to the study.

    Pterostilbene can be taken at any time throughout the day. It should be taken with a meal that contains healthy fats such as avocado or olive oil; this will help increase absorption into the body.

    Also, if you are taking It with NAD boosters, we recommend taking them together in the morning.

    As there are no human clinical or randomised controlled trials indicating that combining these two products is safe we recommend that you choose either Resveratrol or Pterostilbene when trying to increase SIRT1 activity.

    Although not essential, it is recommended that you take your Pterostilbene with a meal that contains a healthy fat. This is because Pterostilbene is fat-soluble, and studies have shown that when similar ingredients are taken with fat, the body’s absorption of the active ingredient can increase by up to 500%.

    Research studies have shown that Piperine can enhance the beneficial effects of Pterostilbene by up to 800%. Grape Seed Extract is added to eliminate the risk of increased cholesterol that may result from taking Pterostilbene alone.

    Certainty of purity.

    We are committed to the following quality controls to ensure consistency, reliability, and transparency in every product. Our goal is to raise industry standards and give you clear reasons to trust what you’re taking.

  • GMP Certified Facility

    All products are made to cGMP (current Good Manufacturing Practice) standards, the global benchmark for supplement quality. GMP standards ensure strict control over how our supplements are produced, covering everything from cleanliness to documentation and quality control. Every step is monitored to guarantee consistency and safety in every batch, so you receive the same high-quality product every time.

  • Third-Party Tested

    At the foundation of what we offer is certainty of product quality through consistent third-party testing, specifically for purity.

  • ISO Quality Managed

    ISO 9001:2015 standards are an internationally recognised framework for effective quality management. This accreditation means we follow a structured system of continuous improvement, always refining our processes to enhance product consistency and customer satisfaction. ISO accreditation ensures that every aspect of our operations, from production to customer service, is optimised. This means better oversight, reduced risk of errors, and a clear focus on delivering consistent results.

  • Transparency

    We believe you should have full clarity about what you’re putting in your body and the steps we take to ensure the quality of our supplements. That’s why we are transparent and open about every part of our process.

    •

    GMP Certified Facility

    Droplets

    Our supplements are manufactured in the UK, at facilities in Oxford and the North of England, following Good Manufacturing Practice (GMP) standards.

    GMP sets requirements for hygiene, production, quality control, and traceability, helping ensure supplements are consistently manufactured under controlled conditions.

    Our manufacturing partners hold independently issued GMP certificates. Rather than simply asking you to take our word for it, we've made these available below for you to review.

    Our UK Manufacturers' GMP Certificates

    Issued by Eurofins and SGS.

    Manufacturer 1

    Manufacturer 2

    Manufacturer names have been redacted for commercial confidentiality.

    Third-Party Tested

    Date • Batch # • Results

    Purity results include Heavy Metals

    Current Batch:

    January 2026

    •

    2501436

    99.5% Purity and Microbiology

    Previous results:

    May 2025

    •

    PB250104 – 2500222

    98.4% Purity and Microbiology

    August 2024

    •

    BN-PB231203

    100% Purity and Microbiology

    December 2023

    •

    PTERO12042023

    99.6% Purity and Microbiology

    April 2023

    •

    PTERO20221101

    98% Purity

    October 2022

    •

    PTERO10202022

    100% Purity

    March 2022

    •

    PTERO03172022

    98% Purity

    March 2021

    •

    PTERO03042021

    98.3% Purity

    December 2019

    •

    PTERO11252019

    99.2% Purity

    ISO Quality Managed

    Vitality Pro is independently certified to ISO 9001:2015, an internationally recognised standard for quality management systems.

    Maintaining this certification requires ongoing monitoring, documented checks, regular reporting and independent audits. These processes help identify areas for improvement, ensure issues are addressed, and continually strengthen the systems and controls behind our supplements. It's a commitment to quality that must be demonstrated and maintained, not simply claimed.

    We believe quality should be independently verified, not simply claimed. You can view our ISO 9001:2015 certificate below.

    Our ISO 9001:2015 Certificate

    View Our Certificate

    Transparency

    We believe you should have full clarity about what you’re putting in your body and the steps we take to ensure the quality of our supplements. That’s why we are transparent and open about every part of our process.

    Transparency means we share all the details that matter—how our products are made, tested, and verified. From publishing third-party test results to offering clear ingredient labels, we provide you with the information you need to make informed choices about your supplements. Nothing is hidden, and every product comes with full accountability.

    In a world where many supplement companies keep you in the dark, we believe you deserve complete honesty. Being transparent allows you to trust that you’re getting exactly what you expect—pure, tested supplements without hidden risks. It’s about empowering you to make confident decisions and focus on your health journey without second-guessing the products you take.

    Trusted By Professionals & Industry Experts

  • Dr. Ahmet Ozyigit

    Dr. Ahmet Ozyigit, MD, MSc, PgDip

    Head of Clinical Research at Elite Hospital

    "As a physician, purity of a product is my main concern when it comes to recommending supplements for my patients. The line of products offered by vitalityPRO is not only in line with the latest research in anti-ageing, but is also third-party tested and purity checked, which is of utmost importance for receiving maximal benefits from treatment."

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    Simon Jones, MBChB, MRCP, MSc

    Lead Academy Doctor at a Premier League Football Club

    "Vitality Pro is a fantastic company, clearly striving to achieve the highest standard and reliability of supplements on the market. Their range really is at the cutting edge of longevity supplements, and the independent third-party testing is incredibly reassuring in terms of quality."

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    Casey Vincent, Two-Time Olympian

    Australian Olympics Sprinter 2000-2004

    “I have done my research on vitalityPRO products and without a doubt have found their supplements to be far superior to the competition”

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    Tony Pemberton, FdENG

    Certified Epigenetic Coach

    "I'm very discerning of either overpriced supplements or poor quality ingredients, but I have to say Vitality PRO products are superb while still being great value. I use them myself for improving ageing biomarkers, and I am happy to recommend them to both my clients and viewership."

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    Elite Athlete Coach

    "I have found Vitality Pro to have a great commitment to the client. They generate trust due to their service, presentation, formulation, technical explanations, and third-party analysis of each of their products. It is a brand that I always recommend when looking for excellence in a product, both for my athletes and for all people looking for supplementation with guarantees."

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    Emel Gunay, DipCNM, mBANT, mIFM

    Nutritional Therapist and Research Manager at OMNOS

    "V​itality-PRO offers excellent customer support, knowledgeable staff, and great value for money on high-quality supplements. ​​The products are of outstanding quality, and I appreciate their dedication to quality and transparency, which ensures safety and compliance for my clients. I​ can highly recommend ​them."

  • Jonny Hirtenstein

    Jonny Hirtenstein, MChiro, DC, ACN

    Founder and Lead Chiropractor at Foundation For Life

    ”As a clinician I appreciate Vitality Pro's passion for producing products that are designed to deliver great results and knowing that they independently test all the batches of the products is very reassuring. Ultimately I know that they care about everything they do, and are striving to produce some of the most cutting edge products on the market.”

  • Dr. Zain Khan

    Dr. Zain Khan, MBBS

    British Medical Association Executive Council Member

    “A professional supplement company who aim to be transparent, innovative and trustworthy. They invest time and money into conducting independent lab tests to verify the purity and quality of their products, ensuring that you receive precisely what you pay for.”

  • Dr James Hetfield

    Dr James Hetfield, Lead Doctor

    Lead Doctor

    Specialise in being a doctor

  • Andy Smith

    Andy Smith, PEMF Expert

    CEO of NewMed & Founder of CELLER8

    "Vitality Pro offers an impressive range of high-quality supplements, and their Magnesium Glycinate is my personal favourite. I love stacking it with my daily PEMF sessions as they complement each other perfectly for enhanced wellness. I trust Vitality Pro for reliable vitamins and supplements, and I’m always happy to recommend them to my customers!"

    •

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    £49.00

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    £25.00

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    £49.00

    The form of AKG used in a landmark study related to lifespan and age-related frailty.
    Cellular Health Longevity Bone Health
  • NMN NMN

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    £49.00

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    Energy Longevity Cellular Health

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    Join vPro+ Rewards for free and earn points when you shop. Turn your points into money off future orders, and earn extra rewards when you introduce a friend.

    • Earn as you shop - collect points on eligible purchases.

    • Enjoy future savings - redeem your points for money off.

    • Share the rewards - give friends a discount and get rewarded when they shop.

    • Keep track easily - view your points and available rewards in your account.

    You can join at checkout while placing your order. Simply create an account, or sign in if you already have one.

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