Vitality Pro
Vitality Pro
Foundational Blood Sugar Energy

Benfotiamine

Foundational
  • Benfotiamine
  • Benfotiamine
  • Benfotiamine
  • Benfotiamine
  • Benfotiamine
    • Benfotiamine
    Benfotiamine
    Benfotiamine
    Benfotiamine
    Benfotiamine

    Third-Party Tested

    GMP Certified Facility

    ISO Quality Managed

    • Why Others Choose Vitality Pro?

    Benfotiamine

    Foundational

    Benfotiamine is a fat-soluble form of thiamine (vitamin B1), which is essential for converting carbohydrates into energy and supporting proper nerve, muscle, and heart function.

    Features

    • 300mg per capsule
    • Take 1 per day
    • Suitable for vegans 
    • Free from common allergens

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    Third-Party Tested

    Date • Batch # • Results

    Purity results include Heavy Metals

    Current Batch:

    November 2025

    •

    2500801

    99% Purity and Microbiology

    Previous results:

    September 2023

    •

    BN2301413

    100% Purity

    GMP Certified Facility

    Our supplements are manufactured in the UK, at facilities in Oxford and the North of England, following Good Manufacturing Practice (GMP) standards.

    GMP sets requirements for hygiene, production, quality control, and traceability, helping ensure supplements are consistently manufactured under controlled conditions.

    Our manufacturing partners hold independently issued GMP certificates. Rather than simply asking you to take our word for it, we've made these available below for you to review.

    Our UK Manufacturers' GMP Certificates

    Issued by Eurofins and SGS.

    Manufacturer 1

    Manufacturer 2

    Manufacturer names have been redacted for commercial confidentiality.

    ISO Quality Managed

    Vitality Pro is independently certified to ISO 9001:2015, an internationally recognised standard for quality management systems.

    Maintaining this certification requires ongoing monitoring, documented checks, regular reporting and independent audits. These processes help identify areas for improvement, ensure issues are addressed, and continually strengthen the systems and controls behind our supplements. It's a commitment to quality that must be demonstrated and maintained, not simply claimed.

    We believe quality should be independently verified, not simply claimed. You can view our ISO 9001:2015 certificate below.

    Our ISO 9001:2015 Certificate

    View Our Certificate

    Recommended Use

    Take one capsule daily with a meal containing healthy fats or as directed by your health care professional.

    Some individuals report that thiamine has a stimulating effect. If you find it difficult to sleep, you may wish to take Benfotiamine with your morning meal.

    Benfotiamine is fat-soluble, meaning it is best absorbed by the body when taken with a fat source. Healthy options for this are avocado, yoghurt, coconut, extra virgin olive oil or any meal containing fat.

    Ingredients

    View supplement label

    Capsules Per Container: 120

    Amount Per Capsule Amount %NRV
    Benfotiamine 300mg *

    Nutrient Reference Value not established*

    Other ingredients (all natural): Microcrystalline Cellulose, Vegetable Cellulose Capsule Shell (HPMC)

    Suitable for vegans. Contains no GMOs, common allergens, artificial colours, preservatives or flavours.

    Storage & Stability

    To maintain the potency and quality of your Benfotiamine, store it in a cool (20°C-25°C), dry place and away from light.

    Quality Standards

    Manufacturing: All products are made to GMP standards and have been quality-managed in accordance with the UK standard ISO 9001:2015. Third-party tested: To ensure the highest purity and maximum effectiveness, each new batch of products undergoes third-party testing by ISO 17025 accreditated Micro Quality Labs. You can view all testing certificates at www.vitality-pro.com/batch-testing.

    Safety & Warnings

    Do not exceed the recommended daily dose. Food supplements should not replace a varied and balanced diet and a healthy lifestyle. If you are pregnant, breastfeeding, under 18 or taking any medication, consult a doctor before use. Stop use if adverse reactions occur.

    Interactions: Benfotiamine and other forms of thiamine are known to interact with the antibiotic Erythromycin and its derivatives Azithromycin and Clarithromycin. If you are taking any medication, please first speak with your doctor before adding Benfotiamine to your supplement regime.

    For further information regarding any other potential drug and supplement interactions with Benfotiamine, please see the ingredient profile on Drug Bank using the link below.* Allergy: This product does not contain any common allergens; however, it should not be used by anyone with a history of hypersensitivity to its ingredients or those taking medications that may interact with it.

    Pregnancy: If pregnant, consult your health professional before using this product.

    *Drug Bank is an independent website that lists potential interactions between the ingredients in Benfotiamine and other medications and supplements. It may not, however, list all known possible interactions. If you are on any medications or supplements you feel may interact negatively with Benfotiamine please first speak with your doctor before using this product.
    1

    Key Studies to Consider

    While individual results may vary due to personal health conditions, genetics, and lifestyle choices, we guarantee that the supplements you receive are made with ingredients of the highest purity, similar to those used in scientific studies, to ensure maximum results.

    Essential Nutrient

     Thiamine – Review

    Dosage: N/A (Focus on the basic functions and deficiency of thiamine)
    Outcome: Overview of how thiamine deficiency affects the body, especially in neurological, cardiac, and gastrointestinal systems.
    Summary: Thiamine is essential for energy metabolism and nervous system health. Deficiency can cause disorders like beriberi and Wernicke-Korsakoff syndrome, especially in individuals with poor nutrition or alcoholism. Regular intake is crucial since thiamine is water-soluble and not stored in large amounts.

    Read more

    Blood Sugar

     The Multifaceted Therapeutic Potential of Benfotiamine – Review

    Dosage: N/A
    Outcome: Effectiveness of benfotiamine in reducing tissue levels of advanced glycation end products (AGEs), which are linked to complications in diabetes such as neuropathy, nephropathy, and retinopathy.
    Summary: Benfotiamine helps reduce harmful compounds in the body that can lead to serious diabetes-related complications. It works by increasing an enzyme that prevents these compounds from forming, showing promise for treating conditions like diabetic nerve, kidney, and eye damage.

    Read more

     Benfotiamine increases glucose oxidation and downregulates NADPH oxidase 4 expression in cultured human myotubes exposed to both normal and high glucose concentrations – Cell Study

    Dosage: Benfotiamine treatment for 4 days
    Outcome: Increase in glucose utilisation and decrease in “NADPH oxidase 4” expression in human muscle cells
    Summary: Benfotiamine was found to boost the breakdown of glucose (sugar) for energy in muscle cells and reduce gene expression linked to oxidative stress under both normal and high sugar conditions. This could be important for managing type 2 diabetes by improving how the body uses sugar and reducing cellular stress.

    Read more

     Detection of transketolase in bone marrow-derived insulin-producing cells: benfotiamine enhances insulin synthesis and glucose metabolism –  Preclinical Animal Study

    Intervention: Benfotiamine treatment in cell cultures and mice
    Outcome: Improved insulin formation and glucose breakdown in bone marrow-derived insulin-producing cells. Helped to normalise levels of blood glucose levels in diabetic mice
    Summary: This study found that benfotiamine boosts insulin production and enhances sugar breakdown in special cells derived from bone marrow, helping to control high blood sugar in diabetic mice.

    Read more

    Energy

     High-dose thiamine improves the symptoms of fibromyalgia – Case report

    Dosage: High doses of thiamine (Vitamin B1)
    Outcome: Improvement in chronic widespread pain and fatigue
    Summary: This study found that taking high doses of thiamine helped reduce chronic pain and fatigue in people with fibromyalgia, suggesting a potential link between thiamine levels and fibromyalgia symptoms.

    Read more

     Thiamine and Fatigue in Inflammatory Bowel Diseases: An Open-Label Pilot Study – Open-Label Pilot Study

    Dosage: High doses of thiamine orally, ranging from 600 mg/day for 60 kg body weight to 1,500 mg/day for 90 kg body weight
    Outcome: Complete or nearly complete regression of fatigue in patients
    Summary: This study found that taking high doses of thiamine significantly reduced fatigue in people with ulcerative colitis and Crohn’s disease, suggesting that the fatigue may be due to a thiamine processing issue in the body rather than a direct deficiency in the blood.

    Read more

    Brain Health

     Benfotiamine prevents increased β-amyloid production in HEK cells induced by high glucose – Cell Study

    Dosage: Benfotiamine in a solution (20 and 40 μg/mL with 5.5 g/L glucose)
    Outcome: Reduction in β-amyloid production in cells
    Summary: High glucose levels were found to increase the production of a substance (β-amyloid) linked to Alzheimer’s disease in specific cells. Adding benfotiamine, at certain doses effectively reduced this increase, possibly by affecting a specific enzyme activity related to the disease process.

    Read more

     Neuroprotective Effects of Thiamine and Precursors with Higher Bioavailability: Focus on Benfotiamine and Dibenzoylthiamine – Review

    Dosage: N/A
    Outcome: Improvement in cognitive outcomes in patients with mild Alzheimer’s disease for Benfotiamine.
    Summary: This study reviews how Benfotiamine and Dibenzoylthiamine, more bioavailable forms of Vitamin B1, can protect the brain. Benfotiamine has been found to help with memory problems in Alzheimer’s without causing harmful effects. Dibenzoylthiamine might be even better, especially at fighting inflammation. These findings are promising for treating brain-related diseases.

    Read more

     Thiamine and benfotiamine improve cognition and ameliorate GSK-3β-associated stress-induced behaviours in mice – Preclinical Animal Study

    Dosage: 200 mg/kg/day of Thiamine or Benfotiamine for 2 weeks
    Outcome: Reduced stress behaviours, improved memory and learning in mice
    Summary: This study found that Thiamine and Benfotiamine can decrease stress-related behaviours and improve learning and memory in mice by affecting an enzyme in the brain called GSK-3β. This suggests they might help fight depression and improve cognition, similar to antidepressants.

    Read more

     Benfotiamine attenuates inflammatory response in LPS stimulated BV-2 microglia – Cell Study

    Dosage: Benfotiamine treatment on immune system cells stimulated with LPS
    Outcome: Reduction in inflammatory markers and increase in anti-inflammatory markers in microglial cells
    Summary: Benfotiamine was found to reduce inflammation in brain immune cells (microglia) when they were activated by a substance that typically causes inflammation (LPS). This could help treat diseases where brain inflammation is a problem.

    Read more

    Everything You Need To Know About Benfotiamine

    Benfotiamine is a synthetic form of thiamine (vitamin B1) that is more bioavailable and better absorbed by the body than regular thiamine. It is fat-soluble, allowing it to penetrate the lipid-rich (fat-based) cell membranes more easily and raise thiamine levels in cells and tissues more effectively. Thiamine plays an essential role in cellular energy production, particularly in carbohydrate metabolism and glucose regulation.

    Once absorbed, benfotiamine is converted into the active form Thiamine.

    Many mechanisms influenced by thiamine stem from its primary role in energy production within the Krebs cycle. Benfotiamine, a form of thiamine, acts as a cofactor (assisting enzymes in biochemical reactions) in the Krebs cycle, supporting the conversion of food, primarily carbohydrates and glucose, into ATP, the body’s primary energy source.

    Thiamine also aids in directing glucose toward pathways that are beneficial for metabolism and energy use. By activating the pentose phosphate pathway (PPP), thiamine directs glucose into routes that support metabolic health and antioxidant production, avoiding those that lead to advanced glycation end-products (AGEs)—harmful compounds that can accumulate in high blood sugar conditions.

    Optimal thiamine levels are essential for energy and blood sugar metabolism, especially in high-energy-demand areas like the brain and muscles. Factors such as ageing, high-carbohydrate diets, alcohol consumption, certain medical conditions, and stress can reduce thiamine levels, impairing glucose metabolism. Without sufficient thiamine, energy production declines, leading to fatigue, weakened cellular function, and reduced brain health.

    Efficient energy metabolism is essential to support cellular repair and function, and chronic high blood sugar and the accumulation of AGEs are linked to age-related decline. By increasing thiamine levels, benfotiamine helps improve energy metabolism and reduce AGE formation, supporting cellular health as we age. Its role in improving glucose metabolism provides energy for cellular function, while reducing oxidative stress may help protect against metabolic and neurological decline commonly seen with ageing.

    Consider the following statements. If you find one or more relatable, Benfotiamine might be the support you’ve been searching for:

    • I want to support my body’s ability to manage blood sugar levels more effectively.
    • I struggle with neuropathy and have read that benfotiamine may help support this condition. 
    • I feel I’m not getting adequate amounts of thiamine in my diet and wish to supplement to avoid a deficiency. 
    • I often feel fatigued and believe that improving my thiamine levels could help me feel more energised.
    • I’ve been diagnosed with low thiamine and wish to use Benfotiamine to help correct my deficiency.
    • I drink alcohol multiple times a week and have read that alcohol consumption can lower thiamine levels. I therefore want to use Benfotiamine to help avoid developing a deficiency. 
    • My doctor has recommended that I utilise Benfotiamine.
    Made to GMP Standards
    ISO 9001 Certified UK Company
    Independent Testing for Purity

    Transparent Testing

    Every batch is independently tested for identity, potency, contaminants, heavy metals, and microbial markers.

    View all product tests

    Benfotiamine test results

    Date • Batch # • Results

    Purity results include Heavy Metals

    Current Batch:

    November 2025

    •

    2500801

    99% Purity and Microbiology

    Previous results:

    September 2023

    •

    BN2301413

    100% Purity

    Frequently Asked Questions

    Yes, they are just different names for the same supplement.

    Benfotiamine is a man-made, fat-soluble form of thiamine. It was developed in Japan in the early 1960s to treat Alcoholic Neuritis. It is thought to be one of the most effective forms of thiamine available.

    Benfotiamine has been found to be safe at dosages of up to 300mg for up to 2 years of consistent use.

    According to Dr Robert Lonsdale, one of the world’s leading experts on thiamine supplementation, some people may initially experience a paradoxical reaction when taking thiamine supplements. A paradoxical reaction is an unexpected response where one may feel slightly worse rather than better initially. This effect is generally temporary and typically subsides within a week or two as the body adjusts.

    True thiamine deficiency is rare; however, individuals who drink alcohol in excess, as well as those who follow a high carbohydrate diet, may require additional thiamine as these substances create a higher demand for thiamine in the body.

    Certainty of purity.

    We are committed to the following quality controls to ensure consistency, reliability, and transparency in every product. Our goal is to raise industry standards and give you clear reasons to trust what you’re taking.

  • GMP Certified Facility

    All products are made to cGMP (current Good Manufacturing Practice) standards, the global benchmark for supplement quality. GMP standards ensure strict control over how our supplements are produced, covering everything from cleanliness to documentation and quality control. Every step is monitored to guarantee consistency and safety in every batch, so you receive the same high-quality product every time.

  • Third-Party Tested

    At the foundation of what we offer is certainty of product quality through consistent third-party testing, specifically for purity.

  • ISO Quality Managed

    ISO 9001:2015 standards are an internationally recognised framework for effective quality management. This accreditation means we follow a structured system of continuous improvement, always refining our processes to enhance product consistency and customer satisfaction. ISO accreditation ensures that every aspect of our operations, from production to customer service, is optimised. This means better oversight, reduced risk of errors, and a clear focus on delivering consistent results.

  • Transparency

    We believe you should have full clarity about what you’re putting in your body and the steps we take to ensure the quality of our supplements. That’s why we are transparent and open about every part of our process.

    •

    GMP Certified Facility

    Our supplements are manufactured in the UK, at facilities in Oxford and the North of England, following Good Manufacturing Practice (GMP) standards.

    GMP sets requirements for hygiene, production, quality control, and traceability, helping ensure supplements are consistently manufactured under controlled conditions.

    Our manufacturing partners hold independently issued GMP certificates. Rather than simply asking you to take our word for it, we've made these available below for you to review.

    Our UK Manufacturers' GMP Certificates

    Issued by Eurofins and SGS.

    Manufacturer 1

    Manufacturer 2

    Manufacturer names have been redacted for commercial confidentiality.

    Third-Party Tested

    Date • Batch # • Results

    Purity results include Heavy Metals

    Current Batch:

    November 2025

    •

    2500801

    99% Purity and Microbiology

    Previous results:

    September 2023

    •

    BN2301413

    100% Purity

    ISO Quality Managed

    Vitality Pro is independently certified to ISO 9001:2015, an internationally recognised standard for quality management systems.

    Maintaining this certification requires ongoing monitoring, documented checks, regular reporting and independent audits. These processes help identify areas for improvement, ensure issues are addressed, and continually strengthen the systems and controls behind our supplements. It's a commitment to quality that must be demonstrated and maintained, not simply claimed.

    We believe quality should be independently verified, not simply claimed. You can view our ISO 9001:2015 certificate below.

    Our ISO 9001:2015 Certificate

    View Our Certificate

    Transparency

    We believe you should have full clarity about what you’re putting in your body and the steps we take to ensure the quality of our supplements. That’s why we are transparent and open about every part of our process.

    Transparency means we share all the details that matter—how our products are made, tested, and verified. From publishing third-party test results to offering clear ingredient labels, we provide you with the information you need to make informed choices about your supplements. Nothing is hidden, and every product comes with full accountability.

    In a world where many supplement companies keep you in the dark, we believe you deserve complete honesty. Being transparent allows you to trust that you’re getting exactly what you expect—pure, tested supplements without hidden risks. It’s about empowering you to make confident decisions and focus on your health journey without second-guessing the products you take.

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    Australian Olympics Sprinter 2000-2004

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