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Take 1-3 capsules per day. This is equal to 10-30 mg of free-form sulforaphane. As it is a powerful detoxifying compound it is advised to build up your dosage slowly over a period of weeks.
For general use, we would not advise taking more than 3 capsules daily. If you require a higher dosage for a specific condition, please consult your doctor before taking more than 3 capsules.
Prostaphane is best taken with a meal to minimise the chance of side effects.
| Amount Per Capsule | Amount | %NRV |
|---|---|---|
| Broccoli Seed Extract | 220mg | |
| Containing: | ||
| Free-Form Stabilised Sulforaphane | 10mg | * |
Nutrient Reference Value not established*
Suitable for vegans. Contains no GMOs, common allergens, artificial colours, preservatives or flavours.
The ideal place to store Prostaphane is in the refrigerator, but it can be kept at room temperature for short periods. When stored at room temperature, the sulforaphane content may slightly decrease to less than 2% or 0.2mg over one month. Refrigeration ensures maximum potency is retained. As a result, there is no need to be concerned if you plan to travel with it.
To find out more information about stability, visit www.vitality-pro.com/prostaphane.
Prostaphane® is a dietary supplement developed by the Olga group, formerly known as Triballat Noyal, a family-owned company based in Noyal-sur-Vilaine, Brittany, France. Established in 1951 by Olga Triballat, the company has a longstanding reputation and complies with all European regulations, adhering to food safety ISO 22002 and HACCP specifications at every step of its manufacturing process. Traceability is ensured from the seed to the boxes. We are honoured to offer it as part of the Vitality Pro range.
We carefully select third-party products with exceptional reputations, verifiable quality controls and adherence to EU and US regulatory standards. Their established quality practices provide a high level of assurance, which allows us to confidently stock their products without additional third-party testing.
Do not exceed the recommended daily dose. Food supplements should not replace a varied and balanced diet and a healthy lifestyle. If you are pregnant, breastfeeding, under 18 or taking any medication, consult a doctor before use. Stop use if adverse reactions occur.
Interactions: Sulforaphane is known to inhibit and induce members of the Cytochrome P450 class of enzymes. As a result, it may interfere with antiplatelet and blood thinning medications such as Warfarin. Higher doses of Sulforaphane may also interact with thyroid function. If you have issues with your thyroid health or if you are taking these medications (or any other medication), please first speak with your doctor before adding Sulforaphane to your supplement regimen.
For further information regarding any other potential drug and supplement interactions of Prostaphane please see the ingredient profile on Drug Bank.*
Allergy: This product does not contain any common allergens; however, it should not be used by anyone with a history of hypersensitivity to its ingredients or those taking medications that may interact with it.
Pregnancy: If pregnant, consult your health professional before using this product.
*Drug Bank is an independent website that lists potential interactions between the ingredients in Prostaphane and other medications and supplements. It may not, however, list all known possible interactions. If you are on any medications or supplements you feel may interact negatively with Prostaphane please first speak with your doctor before using this product.
VitalityPRO are the official distributor of Olga Prostaphane® – the only dietary supplement on the market with free-form stabilised sulforaphane.
Out of stock.
We are very sorry for the further delay. Due to incorrect labelling on new packaging, replacement labels are currently being printed before the new batch can be sent from the manufacturer.
Take 1-3 capsules per day. This is equal to 10-30 mg of free-form sulforaphane. As it is a powerful detoxifying compound it is advised to build up your dosage slowly over a period of weeks.
For general use, we would not advise taking more than 3 capsules daily. If you require a higher dosage for a specific condition, please consult your doctor before taking more than 3 capsules.
Prostaphane is best taken with a meal to minimise the chance of side effects.
| Amount Per Capsule | Amount | %NRV |
|---|---|---|
| Broccoli Seed Extract | 220mg | |
| Containing: | ||
| Free-Form Stabilised Sulforaphane | 10mg | * |
Nutrient Reference Value not established*
Suitable for vegans. Contains no GMOs, common allergens, artificial colours, preservatives or flavours.
The ideal place to store Prostaphane is in the refrigerator, but it can be kept at room temperature for short periods. When stored at room temperature, the sulforaphane content may slightly decrease to less than 2% or 0.2mg over one month. Refrigeration ensures maximum potency is retained. As a result, there is no need to be concerned if you plan to travel with it.
To find out more information about stability, visit www.vitality-pro.com/prostaphane.
Prostaphane® is a dietary supplement developed by the Olga group, formerly known as Triballat Noyal, a family-owned company based in Noyal-sur-Vilaine, Brittany, France. Established in 1951 by Olga Triballat, the company has a longstanding reputation and complies with all European regulations, adhering to food safety ISO 22002 and HACCP specifications at every step of its manufacturing process. Traceability is ensured from the seed to the boxes. We are honoured to offer it as part of the Vitality Pro range.
We carefully select third-party products with exceptional reputations, verifiable quality controls and adherence to EU and US regulatory standards. Their established quality practices provide a high level of assurance, which allows us to confidently stock their products without additional third-party testing.
Do not exceed the recommended daily dose. Food supplements should not replace a varied and balanced diet and a healthy lifestyle. If you are pregnant, breastfeeding, under 18 or taking any medication, consult a doctor before use. Stop use if adverse reactions occur.
Interactions: Sulforaphane is known to inhibit and induce members of the Cytochrome P450 class of enzymes. As a result, it may interfere with antiplatelet and blood thinning medications such as Warfarin. Higher doses of Sulforaphane may also interact with thyroid function. If you have issues with your thyroid health or if you are taking these medications (or any other medication), please first speak with your doctor before adding Sulforaphane to your supplement regimen.
For further information regarding any other potential drug and supplement interactions of Prostaphane please see the ingredient profile on Drug Bank.*
Allergy: This product does not contain any common allergens; however, it should not be used by anyone with a history of hypersensitivity to its ingredients or those taking medications that may interact with it.
Pregnancy: If pregnant, consult your health professional before using this product.
*Drug Bank is an independent website that lists potential interactions between the ingredients in Prostaphane and other medications and supplements. It may not, however, list all known possible interactions. If you are on any medications or supplements you feel may interact negatively with Prostaphane please first speak with your doctor before using this product.
Orders placed are shipped within 24 hours (Monday to Friday) from the UK.
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While individual results may vary due to personal health conditions, genetics, and lifestyle choices, we guarantee that the supplements you receive are made with ingredients of the highest purity, similar to those used in scientific studies, to ensure maximum results.
Induction of Phase 2 Antioxidant Enzymes by Broccoli Sulforaphane: Perspectives in Maintaining Antioxidant Activity of Vitamins A, C, and E – Review
Outcome: Sulforaphane activates the NRF2/Keap1 pathway, boosting detoxification and antioxidant enzymes like NQO1 and GST.
Summary: Sulforaphane supports the body’s detoxification by triggering the KEAP1/NRF2 pathway, which activates phase II enzymes that neutralise harmful substances and oxidative stress.
Sulforaphane Augments Glutathione and Influences Brain Metabolites in Human Subjects – Clinical Pilot Study
Dosage: Daily oral administration at 100 micromoles of sulforaphane for 7 days
Outcome: Increased glutathione levels in blood and brain regions, particularly in the thalamus
Summary: This study found that sulforaphane boosted glutathione levels in both the blood and the brain, suggesting potential benefits for brain health by addressing oxidative stress.
Sulforaphane Restores Cellular Glutathione Levels and Reduces Chronic Periodontitis Neutrophil Hyperactivity – Cell Study
Dosage: Variable doses of 1, 2, 5, 10 or 15µM of Sulforaphane for r 2, 4, 8, 16 and 24hrs.
Outcome: Sulforaphane increased glutathione levels and reduced the overactive response of the immune system in chronic periodontitis.
Summary: Sulforaphane improved glutathione levels and reduced immune system hyperactivity, suggesting it may help regulate inflammation in chronic periodontitis by boosting antioxidant pathways.
Sulforaphane is Anticonvulsant and Improves Mitochondrial Function – Experimental Research
Dosage: Daily injections of sulforaphane for 5 days
Outcome: Increased seizure thresholds, enhanced antioxidant defences, and improved mitochondrial function, but did not prevent cell death in the hippocampus.
Summary: Sulforaphane, a compound that activates certain protective pathways in the brain, was found to help prevent seizures in mouse models of epilepsy and boost the brain’s antioxidant defences. It also improved the energy-producing capabilities of brain cells, although it couldn’t stop cell death caused by severe seizures.
Effects of sulforaphane on brain mitochondria: mechanistic view and future direction – Review
Dosage: N/A
Outcome: Sulforaphane supports mitochondrial function by reducing oxidative stress and promoting mitochondrial health in brain cells.
Summary: Sulforaphane may protect brain mitochondria by enhancing antioxidant defences and reducing cell death caused by oxidative stress. This makes it a potential agent for supporting mitochondrial health, though more research is needed to understand its effects fully.
Sulforaphane inhibits TGF-β-induced fibrogenesis and inflammation in human Tenon’s fibroblasts – Cell Study
Dosage: 0.3 to 10 µM of Sulforaphane applied to cells for 3 days
Outcome: Reduced scar tissue formation and inflammation in eye cells
Summary: Sulforaphane was shown to prevent scar tissue formation and reduce inflammation in eye cells related to glaucoma surgery. This suggests it could help improve the success rate of such surgeries.
Sulforaphane Alleviates Psoriasis by Enhancing Antioxidant Defense through KEAP1-NRF2 Pathway Activation and Attenuating Inflammatory Signaling – Preclinical Animal Study
Dosage: Sulforaphane treatment on a mouse model of psoriasis
Outcome: Improvement in psoriasis symptoms in mice
Summary: This study found that a compound called sulforaphane, found in vegetables like broccoli, can help improve skin symptoms in mice with a condition similar to psoriasis. It works by boosting the body’s defence system against damage and reducing skin inflammation. This suggests that sulforaphane could be a potential treatment for psoriasis in humans.
Sulforaphane is a naturally occurring compound found in cruciferous vegetables such as broccoli, Brussels sprouts, and kale. It is a sulfur-rich compound produced when the enzyme myrosinase converts glucoraphanin into sulforaphane upon chewing or chopping the vegetables.
Whilst all other supplements on the market are only a combination of the precursors of sulforaphane (myrosinase and glucoraphanin) and do not contain actual sulforaphane, Prostaphane® is the only stabilised, free-form sulforaphane supplement available on the market.
Sulforaphane activates the Nrf2 pathway, a defence mechanism against oxidative stress, by modifying a protein that typically binds and degrades Nrf2. This releases Nrf2, enabling it to bind to antioxidant response elements and switch on over 200 protective genes, including those that produce glutathione, a major antioxidant and detoxifier.
The Nrf2 pathway also regulates Phase I and II enzymes’ detoxification activity. Phase I enzymes transform substances into reactive molecules, which can potentially become toxins. Sulforaphane has been shown to reduce Phase I enzyme activity, thereby limiting toxin formation. Additionally, sulforaphane activates Phase II detoxification enzymes, such as those involved in glutathione production, which neutralise these reactive molecules and other toxins. These Phase II enzymes modify toxins to make them water-soluble so they can be more easily removed from the body.
Sulforaphane forms when myrosinase, an enzyme, combines with glucoraphanin in cruciferous vegetables. This happens when the vegetables are chewed or chopped. However, the process is sensitive to environmental factors such as pH, heat, and storage conditions, which can degrade myrosinase and reduce sulforaphane production. Gut bacteria can also contribute to this conversion, but their effectiveness varies based on an individual’s microbiome health and gut function.
Most sulforaphane supplements only contain precursors like glucoraphanin and myrosinase, requiring conversion within the gut to produce active sulforaphane. However, this conversion depends heavily on individual factors such as microbiome health, gut pH, and enzyme activity, all of which can vary significantly from person to person. If these conditions are not optimal, the conversion may be inefficient, leading to reduced sulforaphane production and limiting the supplement’s effectiveness.
Prostaphane® is unique as the only supplement that offers free-form, stabilised sulforaphane, ensuring up to 70% bioavailability, compared to significantly lower levels in supplements that only contain precursors like glucoraphanin and myrosinase. This high bioavailability guarantees that users receive a consistent and effective dose of sulforaphane. Prostaphane® has been clinically proven to be more effective.
Healthy cells maintain a balance between the production of reactive oxygen species (ROS) and the body’s ability to neutralise them with antioxidants. Overproduction of ROS, caused by environmental factors like pollution or poor diet, leads to oxidative stress, which damages cells.
Efficient detoxification supports the removal of harmful compounds and metabolic byproducts. Enzyme function in detoxification pathways can decline due to accumulated cellular damage, reduced nutrient intake, and decreased enzymatic activity. Compromised detoxification can lead to increased oxidative damage, inflammation, and impaired cellular repair.
By the age of 40–50, Nrf2 activity and antioxidant enzyme production can decline due to factors such as oxidative stress buildup, metabolism slowdown, and reduced cellular repair mechanisms. Sustained Nrf2 function aids in cellular repair and resilience, limiting the accumulation of damage over time. This protection supports cognitive health, metabolic balance, and the maintenance of joint and muscle function, maintaining physical and cognitive ability as we age.
Consider the following statements. If you find one or more relatable, Prostaphane might be the support you’ve been searching for:
Prostaphane is likely safe for people with thyroid issues, however, some literature does indicate that some of the chemicals in Prostaphane might slow iodine transport by the thyroid. Iodine is required by the thyroid to make thyroid hormones. If you have any form of thyroid disease, please first consult with your doctor before choosing to take Prostaphane.
We recommend that you stick to a maximum of 3 capsules of Prostaphane a day unless under the supervision of a doctor. This will provide between 10 and 30 mg of free-form sulforaphane.
Sometimes referred to as a Herxheimer, a detox reaction occurs when the body starts to release stored chemicals faster than it can excrete them. For the most part, these are not harmful and will pass a few days after starting Prostaphane supplementation. Symptoms of a detox reaction include fatigue, headache and joint discomfort. To reduce the chances of developing a detox reaction we suggest that you start on one capsule of Prostphane and slowly increase your dosage.
Prostaphane® utilises a patented process to stabilise free-form sulforaphane. This process involves complexing sulforaphane with cyclodextrins, which are cyclic oligosaccharides. The inclusion of sulforaphane within the hydrophobic cavity of cyclodextrins protects it from degradation by stomach acid, thereby enhancing its stability and bioavailability. Studies have shown that such cyclodextrin complexes can preserve the biological activity of sulforaphane even at elevated storage temperatures .
This stabilisation technique allows Prostaphane® to deliver a consistent and bioavailable dose of sulforaphane without the need for enteric coating. Clinical data indicate that Prostaphane® achieves approximately 70% bioavailability, which is significantly higher than the 10% typically observed with precursor-based supplements containing glucoraphanin and myrosinase.
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