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For best results, take 2-3 capsules per day, or as directed by your health care professional.
GlyNAC is best taken on an empty stomach, away from meals, to ensure optimal absorption by avoiding competition for uptake with other amino acids from food
GlyNAC is also a potent antioxidant and may blunt some of the positive effects of resistance or weight training exercise, we therefore recommend that you do not take GlyNAC around these sessions.
| Amount Per Capsule | Amount | %NRV |
|---|---|---|
| Glycine | 350mg | * |
| N-Acetyl Cysteine (NAC) | 350mg | * |
Nutrient Reference Value not established*
Suitable for vegans. Contains no GMOs, common allergens, artificial colours, preservatives or flavours.
Date · Batch # · Results
Purity results include Heavy Metals
NAC · 2600448
98.8% Purity and Microbiology
Previous results:
December 2025
Glycine · 2501129
98.7% Purity and Microbiology
NAC · 2501129
101.2% Purity and Microbiology
August 2024
Glycine · 2400213
99.7% Purity and Microbiology
NAC · 2400213
99.1% Purity and Microbiology
April 2024
Glycine · 202430411
99.6% Purity and Microbiology
NAC · 2301112
99.1% Purity and Microbiology
September 2023
Glycine · 09062023
99.4% Purity
NAC · 09062023
99.1% Purity
November 2022
Glycine · 11032022
99.8% Purity
NAC · 11032022
95.7% Purity
Testing is carried out by Certified Labs (formerly Micro Quality Labs).
To maintain the potency and quality of your GlyNAC supplements, store them in a cool (20°C-25°C), dry place and away from light.
Manufacturing: All products are made to GMP standards and have been quality-managed in accordance with the UK standard ISO 9001:2015.
Third-party tested: To ensure the highest purity and maximum effectiveness, each new batch of products undergoes third-party testing by ISO 17025 accreditated Micro Quality Labs. You can view all testing certificates at www.vitality-pro.com/batch-testing.
Do not exceed the recommended daily dose. Food supplements should not replace a varied and balanced diet and a healthy lifestyle. If you are pregnant, breastfeeding, under 18 or taking any medication, consult a doctor before use. Stop use if adverse reactions occur.
Interactions: GlyNAC may have antiplatelet and anticoagulant effects, potentially increasing the risk of bleeding when taken with blood thinners such as Warfarin and Clopidogrel. GlyNAC may also increase the effects of the heart medications Nitroglycerin and Isosorbide, as well as the antifungal medication Oxiconazole. If you are taking these medications or any other medication, please first speak with your doctor before adding GlyNAC to your supplement regime.
For further information regarding any other potential drug and supplement interactions with GlyNAC please see the individual ingredient profiles on Drug Bank using the links below.*
Allergy: This product does not contain any common allergens; however, it should not be used by anyone with a history of hypersensitivity to its ingredients or those taking medications that may interact with it.
Pregnancy: If pregnant, consult your health professional before using this product.
*Drug Bank is an independent website that lists potential interactions between the ingredients in GlyNAC and other medications and supplements. It may not, however, list all known possible interactions. If you are taking any medications or supplements that you feel may interact negatively with Apigenin, please speak with your doctor before using this product.
GlyNAC combines glycine and N-acetylcysteine to provide the building blocks for glutathione, the body’s master antioxidant and detoxifier. Research suggests that taking these amino acids together enhances glutathione production more effectively than taking them separately.
For best results, take 2-3 capsules per day, or as directed by your health care professional.
GlyNAC is best taken on an empty stomach, away from meals, to ensure optimal absorption by avoiding competition for uptake with other amino acids from food
GlyNAC is also a potent antioxidant and may blunt some of the positive effects of resistance or weight training exercise, we therefore recommend that you do not take GlyNAC around these sessions.
| Amount Per Capsule | Amount | %NRV |
|---|---|---|
| Glycine | 350mg | * |
| N-Acetyl Cysteine (NAC) | 350mg | * |
Nutrient Reference Value not established*
Suitable for vegans. Contains no GMOs, common allergens, artificial colours, preservatives or flavours.
Date · Batch # · Results
Purity results include Heavy Metals
NAC · 2600448
98.8% Purity and Microbiology
Previous results:
December 2025
Glycine · 2501129
98.7% Purity and Microbiology
NAC · 2501129
101.2% Purity and Microbiology
August 2024
Glycine · 2400213
99.7% Purity and Microbiology
NAC · 2400213
99.1% Purity and Microbiology
April 2024
Glycine · 202430411
99.6% Purity and Microbiology
NAC · 2301112
99.1% Purity and Microbiology
September 2023
Glycine · 09062023
99.4% Purity
NAC · 09062023
99.1% Purity
November 2022
Glycine · 11032022
99.8% Purity
NAC · 11032022
95.7% Purity
Testing is carried out by Certified Labs (formerly Micro Quality Labs).
To maintain the potency and quality of your GlyNAC supplements, store them in a cool (20°C-25°C), dry place and away from light.
Manufacturing: All products are made to GMP standards and have been quality-managed in accordance with the UK standard ISO 9001:2015.
Third-party tested: To ensure the highest purity and maximum effectiveness, each new batch of products undergoes third-party testing by ISO 17025 accreditated Micro Quality Labs. You can view all testing certificates at www.vitality-pro.com/batch-testing.
Do not exceed the recommended daily dose. Food supplements should not replace a varied and balanced diet and a healthy lifestyle. If you are pregnant, breastfeeding, under 18 or taking any medication, consult a doctor before use. Stop use if adverse reactions occur.
Interactions: GlyNAC may have antiplatelet and anticoagulant effects, potentially increasing the risk of bleeding when taken with blood thinners such as Warfarin and Clopidogrel. GlyNAC may also increase the effects of the heart medications Nitroglycerin and Isosorbide, as well as the antifungal medication Oxiconazole. If you are taking these medications or any other medication, please first speak with your doctor before adding GlyNAC to your supplement regime.
For further information regarding any other potential drug and supplement interactions with GlyNAC please see the individual ingredient profiles on Drug Bank using the links below.*
Allergy: This product does not contain any common allergens; however, it should not be used by anyone with a history of hypersensitivity to its ingredients or those taking medications that may interact with it.
Pregnancy: If pregnant, consult your health professional before using this product.
*Drug Bank is an independent website that lists potential interactions between the ingredients in GlyNAC and other medications and supplements. It may not, however, list all known possible interactions. If you are taking any medications or supplements that you feel may interact negatively with Apigenin, please speak with your doctor before using this product.
Orders placed are shipped within 24 hours (Monday to Friday) from the UK.
Need some advice?
Customer Care | +44 (0) 1202 082 280 | support@vitality-pro.com
While individual results may vary due to personal health conditions, genetics, and lifestyle choices, we guarantee that the supplements you receive are made with ingredients of the highest purity, similar to those used in scientific studies, to ensure maximum results.
Supplementing Glycine and N-Acetylcysteine (GlyNAC) in Older Adults Improves Glutathione Deficiency, Oxidative Stress, Mitochondrial Dysfunction, Inflammation, Physical Function, and Aging Hallmarks – Randomised Control Trial
Dosage: GlyNAC (Glycine and N-Acetylcysteine) supplementation for 16 weeks in older adults
Outcome: Improvement in glutathione production, reduced oxidative stress, improved mitochondrial function, and better physical function in older adults.
Summary: GlyNAC supplementation for 16 weeks helped older adults increase glutathione levels, which in turn reduced oxidative stress and improved various ageing-related issues like mitochondrial dysfunction and physical decline.
GlyNAC (Glycine and N-Acetylcysteine) Supplementation Improves Impaired Mitochondrial Fuel Oxidation and Lowers Insulin Resistance in Patients with Type 2 Diabetes – Pilot Study
Dosage: GlyNAC (Glycine and N-Acetylcysteine) supplementation for 14 days
Outcome: Improvement in mitochondrial function and reduction in insulin resistance
Summary: In people with type 2 diabetes, a 14-day course of GlyNAC (a combination of two supplements) helped improve the function of mitochondria (the energy-producing parts of cells) and reduced insulin resistance, making it easier for their bodies to control blood sugar levels.
GlyNAC (Glycine and N-Acetylcysteine) Supplementation in Mice Increases Length of Life by Correcting Glutathione Deficiency, Oxidative Stress, Mitochondrial Dysfunction, Abnormalities in Mitophagy and Nutrient Sensing, and Genomic Damage – Preclinical Animal Study
Dosage: GlyNAC supplementation in mice
Outcome: Increased lifespan by 24%
Summary: Giving mice a GlyNAC supplement made them live 24% longer. It worked by fixing issues related to ageing, like damage from oxidative stress, mitochondrial problems, and decreases in a protective antioxidant called glutathione. This suggests that GlyNAC could help improve both lifespan and health quality, showing the potential for further research in nutritional supplements to enhance longevity.
Supplementing Glycine and N-Acetylcysteine (GlyNAC) in Older Adults Improves Glutathione Deficiency, Oxidative Stress, Mitochondrial Dysfunction, Inflammation, Physical Function, and Aging Hallmarks -Randomised Clinical Trial
Dosage: 100 mg/kg/day of glycine and 100 mg/kg/day of N-acetylcysteine (GlyNAC) for 16 weeks
Outcome: Improvements in glutathione levels, oxidative stress, mitochondrial function, inflammation, physical performance, and markers of ageing
Summary: GlyNAC supplementation in older adults over 16 weeks improved multiple markers of ageing, including better physical function, reduced oxidative stress, and improved mitochondrial and cellular health. No significant changes were seen in the placebo group.
Glycine and N-acetylcysteine (GlyNAC) supplementation in older adults improves various health markers: Results of a pilot clinical trial – Pilot Clinical Trial
Dosage: GlyNAC supplementation for 24 weeks
Outcome: Improvement in antioxidant levels, reduction in oxidative stress and inflammation, better mitochondrial function, insulin sensitivity, muscle strength, cognition, and overall health markers.
Summary: This study found that taking a supplement combining glycine and N-acetylcysteine for six months helped older adults by boosting their antioxidant levels, reducing stress on their cells, improving their insulin sensitivity, and enhancing muscle strength and brain function. However, these benefits decreased after stopping the supplement for three months.
GlyNAC (Glycine and N-Acetylcysteine) Supplementation in Old Mice Improves Brain Health – Preclinical Animal Study
Intervention: GlyNAC supplementation for 8 weeks
Outcome: Improved cognitive function and brain health
Summary: In older mice, supplementing with GlyNAC for 8 weeks improved brain health and reversed age-related cognitive decline by fixing brain issues like antioxidant levels, energy production, and inflammation. This suggests GlyNAC could help keep the brain healthy as it ages.
N-acetylcysteine ameliorates chemotherapy-induced impaired anxiety and depression-like behaviors by regulating inflammation, oxidative and cholinergic status, and BDNF release – Animal study
Dosage: Methotrexate (chemotherapy drug) at 100 mg/kg once, followed by N-acetylcysteine (NAC) at 500 mg/kg in two doses
Outcome: Improvement in anxiety and depression-like behaviors in rats
Summary: This study found that N-acetylcysteine helped improve mood problems like anxiety and depression in rats caused by chemotherapy. NAC works by reducing inflammation, balancing chemicals in the brain, and improving the body’s antioxidant levels.
Effects of N-acetylcysteine on Oxidative Stress Biomarkers, Depression, and Anxiety Symptoms in Patients with Multiple Sclerosis – Clinical Trial
Dosage: 600 mg of N-acetylcysteine (NAC) taken twice daily for 8 weeks
Outcome: Decrease in markers of oxidative stress and anxiety symptoms; no significant change in depression symptoms
Summary: This study found that taking NAC twice a day for two months helped reduce stress markers in the body and improved feelings of anxiety in people with multiple sclerosis. However, it didn’t significantly help with depression symptoms.
GlyNAC is a combination of glycine and N-acetylcysteine (NAC), two amino acid precursors required for the production of glutathione, the body’s most powerful antioxidant. Glutathione plays an essential role in protecting cells from oxidative stress and helping detoxify the body.
GlyNAC is converted to glutathione through a series of biochemical steps involving its two components, glycine and N-acetylcysteine (NAC), plus glutamate, which is typically highly present in cells.
Once glutathione is formed, it functions by neutralising reactive oxygen species (ROS), harmful molecules generated as byproducts of normal biological processes and environmental stressors. It does this through a process called a redox reaction. It donates an electron to unstable ROS, stabilising them and converting harmful ROS into water or other less harmful molecules. In addition to its antioxidant role, glutathione is crucial for detoxification. Glutathione binds to toxins in the liver and helps convert them into water-soluble forms, making them easier for the body to eliminate.
Healthy glutathione levels are essential for neutralising reactive oxygen species (ROS) and maintaining cellular health. However, with age, stress, or disease, glutathione levels decline, making the body more vulnerable to oxidative stress and toxin buildup, which leads to cellular damage.
The liver relies on glutathione for detoxification, particularly during Phase II. This is where glutathione binds to harmful substances like heavy metals and pesticides, making them water-soluble for safe elimination. Declines in glutathione impair detoxification, contributing to toxin accumulation, oxidative stress, and inflammation.
As we age, glutathione levels decline due to reduced availability of its precursors, increased demand, depleting reserves, and less efficient recycling. GlyNAC may protect cells from oxidative damage by boosting glutathione, which supports cellular health and enhances detoxification. Studies suggest that higher glutathione levels are linked to greater longevity and a lower risk of age-related diseases.
Consider the following statements. If you find one or more relatable, GlyNAC might be the support you’ve been searching for:
We are committed to the following quality controls to ensure consistency, reliability, and transparency in every product. Our goal is to raise industry standards and give you clear reasons to trust what you’re taking.
All products are made to cGMP (current Good Manufacturing Practice) standards, the global benchmark for supplement quality. GMP standards ensure strict control over how our supplements are produced, covering everything from cleanliness to documentation and quality control. Every step is monitored to guarantee consistency and safety in every batch, so you receive the same high-quality product every time.
Created by the US FDA, GMP regulations legally require manufacturers to ensure product safety, purity, and effectiveness. GMP minimises contamination, mix-ups, and errors, protecting consumers from ineffective or unsafe products.
GMP Guidelines Overview:
At the foundation of what we offer is certainty of product quality through consistent third-party testing, specifically for purity.
In an industry where many supplement providers cannot be fully certain of their product quality, third-party testing is essential to ensure purity and safety. This process removes uncertainty, so you can be confident that you’re taking supplements that are both safe and effective.
Every active ingredient in every batch of vitalityPRO products is independently tested by accredited laboratories to ensure unbiased analysis of purity.
Additional third-party testing screens for contaminants such as heavy metals, pesticides, and microbes, ensuring that each product is safe for consumption. Although certificates are provided by the manufacturer, this independent validation goes beyond standard testing, adding an extra layer of quality control.
Independent third-party testing ensures that you receive reliable, high-quality products every time.
ISO 9001:2015 standards are an internationally recognised framework for effective quality management. This accreditation means we follow a structured system of continuous improvement, always refining our processes to enhance product consistency and customer satisfaction. ISO accreditation ensures that every aspect of our operations—from production to customer service—is optimised. This means better oversight, reduced risk of errors, and a clear focus on delivering consistent results.
ISO 9001:2015 accreditation highlights a commitment to quality, customer satisfaction, and continuous improvement.
We believe you should have full clarity about what you’re putting in your body and the steps we take to ensure the quality of our supplements. That’s why we are transparent and open about every part of our process.
Transparency means we share all the details that matter—how our products are made, tested, and verified. From publishing third-party test results to offering clear ingredient labels, we provide you with the information you need to make informed choices about your supplements. Nothing is hidden, and every product comes with full accountability.
As NAC is an organic compound containing sulphur, GlyNAC will have an odour. This is completely normal.
NAC is taken to support the body’s production of the anti-oxidant Glutathione. However, the amino acid Glycine is also required to produce this antioxidant, and it is often deficient in the diet. Combining these two amino acids gives the body the building blocks it needs for optimal glutathione production.
The answer depends. Some people have genetic issues that prevent them from making optimal amounts of glutathione in which case a reduced glutathione supplement may be the better option. However many people experience significant side effects from supplemental glutathione. In this case, GlyNAC supplementation along with other anti-oxidants such as Vitamin E and Selenium is recommended.
GlyNAC has been used in studies at doses as high as 7.2 grams a day; however, this was done in a controlled setting and for a short period of time. Dosages of 1.4 to 2.1 grams (2-3 capsules) have a better safety record and are also less likely to result in side effects. To assess your tolerance, we suggest starting with one capsule a day and working up from there.
Whilst uncommon, side effects of GlyNAC include nausea, fatigue, upset stomach, and headache. If you experience side effects while taking GlyNAC, we suggest that you lower your dosage.
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