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Fisetin is a flavonoid, a unique class of polyphenols believed to prevent disease and encourage healthy ageing through potent antioxidant and anti-inflammatory effects, as well as its function as a senolytic. This compound may prevent age-related disease by promoting natural cellular senescence.
- Fisetin (100mg) per capsule
- 60 capsules per bottle
- Natural Fisetin derived from Cotinus Coggygria
- Third-party lab tested for purity – certificates attached
- Contains no GMOs, artificial colours, preservatives, flavours or allergens
- Suitable for vegans
- 100% biodegradable packaging
For best results, take 1-2 capsule per day with water, or as directed by your health care professional. This is equal to 100mg – 200mg of Fisetin.
Additional ingredients: Vegetable Cellulose (Capsule), Microcrystalline Cellulose (100% Natural Filler)
*All Vitality Pro products are manufactured and third-party tested to GMP standards and ISO 9001:2015 quality certified.
One of the most successful approaches to counteract ageing is clearing senescent cells, harmful cells from our body that can cause some age-related diseases.
A new triterpenoid compound from the flavonoid family, Fisetin, is thought to help clear these senescent cells from the body.
In a study by Unity Biotechnology with mice, scientists showed that Fisetin could clear senescent cells and has beneficial effects on health span.
Fisetin is absorbed quickly and completely after oral administration due to structural similarities to many dietary flavonoids like Quercetin or Kaempferol. This makes it likely that Fisetin will be perfectly able to pass through the gut barrier of humans.
The study’s scientists used a mouse model whose livers showed an age-related increase in liver scarring (fibrosis). They found that Fisetin ameliorates these changes and restores normal morphology even with such a short time frame. Dr Henning U. Lohmann, the Head of Research at Unity Biotechnology, who directed the study, said, “This type of treatment can reverse disease progression and has huge implications for patients suffering from chronic hepatic diseases”.
One other interesting observation made during the experiment was that Fisetin not only leads to the elimination of senescent cells but also makes young cells age slower. The scientists observed this in so-called “epithelial” cell cultures – which our organs are made of. These experiments also confirmed that Fisetin affects liver healthspan and fibrosis.
In conclusion, Fisetin is a promising senolytic, and it will be exciting to see whether this compound will become the next big thing in life extension.
Fisetin acts as a senotherapeutic by targeting critical genes involved in cellular senescence and ageing.