Phone: +44 (0) 1282 480 480
Email: support@vitality-pro.com
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For best results, split this bundle up into AM and PM dosing schedules.
AM
Both of the supplements can be taken with or without food.
PM
Trans Resveratrol should be taken alongside a meal containing health fats such as olive oil or yoghurt. We recommend that you take Spermidine last thing at night before bed to improve cellular clean up and autophagy.
| Amount Per Capsule | Amount | %NRV |
|---|---|---|
| Magtein® Magnesium Threonate | 667mg | * |
| Fully reacted | ||
| Providing 48mg Elemental Magnesium |
* | 12.8% |
Nutrient Reference Value not established*
| Amount Per Capsule | Amount | %NRV |
|---|---|---|
| PQQ | 20mg | * |
| Pyrroloquinoline Quinone |
Nutrient Reference Value not established*
Suitable for vegans. Contains no GMOs, common allergens, artificial colours, preservatives or flavours.
| Amount Per Capsule | Amount | %NRV |
|---|---|---|
| Spermidine | >4mg | * |
| from Wheat Germ Extract, a natural source |
Nutrient Reference Value not established*
Contains no GMOs, artificial colours, preservatives or flavours. Contains GLUTEN.
Suitable for vegans. See allergens in bold.
| Amount Per Capsule | Amount | %NRV |
|---|---|---|
| Trans Resveratrol | 500mg | * |
| from Japanese Knotweed, natural source |
Nutrient Reference Value not established*
Suitable for vegans. Contains no fillers, GMOs, common allergens, artificial colours, preservatives or flavours.
Please see our product testing page for the most up-to-date testing on each product.
You can find our product testing page here.
To maintain the potency and quality of your vitalityPRO mitochondria support bundle, store them in a cool (20°C-25°C), dry place, and away from light.
Manufacturing: All products are made to GMP standards and have been quality-managed in accordance with the UK standard ISO 9001:2015.
Third-party tested: To ensure the highest purity and maximum effectiveness, each new batch of products undergoes third-party testing by ISO 17025 accreditated Micro Quality Labs. You can view all testing certificates at www.vitality-pro.com/batch-testing.
Do not exceed the recommended daily dose. Food supplements should not replace a varied and balanced diet and a healthy lifestyle. If you are pregnant, breastfeeding, under 18 or taking any medication, consult a doctor before use. Stop use if adverse reactions occur.
Interactions: Bisphosphonates are used to treat osteoporosis. Magnesium can interfere with the absorption of bisphosphonates if taken too closely together. It’s generally recommended to take magnesium supplements at a different time of day than bisphosphonates to avoid this interaction. Some forms of antibiotics, especially quinolone antibiotics (like Ciprofloxacin) and tetracycline antibiotics, can have their absorption reduced by magnesium. To avoid this, take magnesium supplements at least 2 hours before or after the antibiotic. Magnesium has been shown to interfere with the absorption of thyroid medications including Levothyroxine, Liothyronine and Naturally Dessecated Thyroid (NDT) preparations. Aim to take magnesium supplements at least 2 hours away from any thyroid medication you may be taking.
If you are taking these medications or any other medication, please first speak with your doctor before adding Magnesium Threonate to your supplement regime.
For further information regarding any other potential drug and supplement interactions of Magnesium Threonate please see the ingredient profile on Drug Bank.*
Allergy: This product does not contain any common allergens; however, it should not be used by anyone with a history of hypersensitivity to its ingredients or those taking medications that may interact with it.
Pregnancy: If pregnant, consult your health professional before using this product.
*Drug Bank is an independent website that lists potential interactions between the ingredients in Magnesium Threonate and other medications and supplements. It may not, however, list all known possible interactions. If you are on any medications or supplements you feel may interact negatively with Magnesium Threonate please first speak with your doctor before using this product.
Do not exceed the recommended daily dose. Food supplements should not replace a varied and balanced diet and a healthy lifestyle. If you are pregnant, breastfeeding, under 18 or taking any medication, consult a doctor before use. Stop use if adverse reactions occur.
Interactions: It is unclear whether or not PQQ interacts with any medications or not. PQQ does however, increase levels of anti-oxidants produced by the body, such as Glutathione, which may have a negative effect on certain chemo-therapeutics. If you are taking any chronic medications please or any other medication, please first speak with your doctor before adding PQQ to your supplement regime
For further information regarding any other potential drug and supplement interactions of PQQ please see the ingredient profile on Drug Bank.*
Allergy: This product does not contain any common allergens; however, it should not be used by anyone with a history of hypersensitivity to its ingredients or those taking medications that may interact with it.
Pregnancy: If pregnant, consult your health professional before using this product.
*Drug Bank is an independent website that lists potential interactions between the ingredients in PQQ and other medications and supplements. It may not, however, list all known possible interactions. If you are on any medications or supplements you feel may interact negatively with PQQ please first speak with your doctor before using this product.
Do not exceed the recommended daily dose. Food supplements should not replace a varied and balanced diet and a healthy lifestyle. If you are pregnant, breastfeeding, under 18 or taking any medication, consult a doctor before use. Stop use if adverse reactions occur.
Interactions: As of 10 November 2024, there are no known published direct interactions between Spermidine and other medications. However, this does not mean interactions do not exist. Spermidine is a supplement that can improve insulin sensitivity; if you take medications and/or other supplements to help manage your blood sugar, you should first speak with your doctor before adding Spermidine to your supplement regime.
For further information regarding any other potential drug and supplement interactions of Spermidine please see the individual ingredient profile on Drug Bank*.
Allergy: This product does not contain any common allergens; however, it should not be used by anyone with a history of hypersensitivity to its ingredients or those taking medications that may interact with it.
Pregnancy: If pregnant, consult your health professional before using this product.
*Drug Bank is an independent website that lists potential interactions between the ingredients in Spermidine and other medications and supplements. It may not, however, list all known possible interactions. If you are taking any medications or supplements you feel may interact negatively with Spermidine please first speak with your doctor before using this product.
Do not exceed the recommended daily dose. Food supplements should not replace a varied and balanced diet and a healthy lifestyle. If you are pregnant, breastfeeding, under 18 or taking any medication, consult a doctor before use. Stop use if adverse reactions occur.
Interactions: Trans-Resveratrol is known to inhibit members of the Cytochrome P450 class of enzymes. As a result, it may interfere with antiplatelet and anticoagulant medications such as Warfarin. Additionally, resveratrol is classed as a phytoestrogen, a plant molecule that can mimic the effects of oestrogen in the body. Therefore, individuals who are hormone replacement therapies should therefore consult with their doctors before adding resveratrol to their longevity protocols. If you are taking these medications or any other medication, please first speak with your doctor before adding Resveratrol to your supplement regime.
For further information regarding any other potential drug and supplement interactions of Trans-Resveratrol, please see the ingredient profile on Drug Bank.*
Allergy: This product does not contain any common allergens; however, it should not be used by anyone with a history of hypersensitivity to its ingredients or those taking medications that may interact with it.
Pregnancy: If pregnant, consult your health professional before using this product.
*Drug Bank is an independent website that lists potential interactions between the ingredients in Trans-Resveratrol and other medications and supplements. It may not, however, list all known possible interactions. If you are on any medications or supplements you feel may interact negatively with Trans-Resveratrol please first speak with your doctor before using this product.
Alex Manos’ Mitochondrial support bundle includes Magnesium Threonate, PQQ, Spermidine and Trans Resveratrol. The bundle aims to support the production of new mitochondria and the repair and maintenance of existing ones.
Includes a month’s supply of:
Free from common allergens. Suitable for vegans.
For best results, split this bundle up into AM and PM dosing schedules.
AM
Both of the supplements can be taken with or without food.
PM
Trans Resveratrol should be taken alongside a meal containing health fats such as olive oil or yoghurt. We recommend that you take Spermidine last thing at night before bed to improve cellular clean up and autophagy.
| Amount Per Capsule | Amount | %NRV |
|---|---|---|
| Magtein® Magnesium Threonate | 667mg | * |
| Fully reacted | ||
| Providing 48mg Elemental Magnesium |
* | 12.8% |
Nutrient Reference Value not established*
| Amount Per Capsule | Amount | %NRV |
|---|---|---|
| PQQ | 20mg | * |
| Pyrroloquinoline Quinone |
Nutrient Reference Value not established*
Suitable for vegans. Contains no GMOs, common allergens, artificial colours, preservatives or flavours.
| Amount Per Capsule | Amount | %NRV |
|---|---|---|
| Spermidine | >4mg | * |
| from Wheat Germ Extract, a natural source |
Nutrient Reference Value not established*
Contains no GMOs, artificial colours, preservatives or flavours. Contains GLUTEN.
Suitable for vegans. See allergens in bold.
| Amount Per Capsule | Amount | %NRV |
|---|---|---|
| Trans Resveratrol | 500mg | * |
| from Japanese Knotweed, natural source |
Nutrient Reference Value not established*
Suitable for vegans. Contains no fillers, GMOs, common allergens, artificial colours, preservatives or flavours.
Please see our product testing page for the most up-to-date testing on each product.
You can find our product testing page here.
To maintain the potency and quality of your vitalityPRO mitochondria support bundle, store them in a cool (20°C-25°C), dry place, and away from light.
Manufacturing: All products are made to GMP standards and have been quality-managed in accordance with the UK standard ISO 9001:2015.
Third-party tested: To ensure the highest purity and maximum effectiveness, each new batch of products undergoes third-party testing by ISO 17025 accreditated Micro Quality Labs. You can view all testing certificates at www.vitality-pro.com/batch-testing.
Do not exceed the recommended daily dose. Food supplements should not replace a varied and balanced diet and a healthy lifestyle. If you are pregnant, breastfeeding, under 18 or taking any medication, consult a doctor before use. Stop use if adverse reactions occur.
Interactions: Bisphosphonates are used to treat osteoporosis. Magnesium can interfere with the absorption of bisphosphonates if taken too closely together. It’s generally recommended to take magnesium supplements at a different time of day than bisphosphonates to avoid this interaction. Some forms of antibiotics, especially quinolone antibiotics (like Ciprofloxacin) and tetracycline antibiotics, can have their absorption reduced by magnesium. To avoid this, take magnesium supplements at least 2 hours before or after the antibiotic. Magnesium has been shown to interfere with the absorption of thyroid medications including Levothyroxine, Liothyronine and Naturally Dessecated Thyroid (NDT) preparations. Aim to take magnesium supplements at least 2 hours away from any thyroid medication you may be taking.
If you are taking these medications or any other medication, please first speak with your doctor before adding Magnesium Threonate to your supplement regime.
For further information regarding any other potential drug and supplement interactions of Magnesium Threonate please see the ingredient profile on Drug Bank.*
Allergy: This product does not contain any common allergens; however, it should not be used by anyone with a history of hypersensitivity to its ingredients or those taking medications that may interact with it.
Pregnancy: If pregnant, consult your health professional before using this product.
*Drug Bank is an independent website that lists potential interactions between the ingredients in Magnesium Threonate and other medications and supplements. It may not, however, list all known possible interactions. If you are on any medications or supplements you feel may interact negatively with Magnesium Threonate please first speak with your doctor before using this product.
Do not exceed the recommended daily dose. Food supplements should not replace a varied and balanced diet and a healthy lifestyle. If you are pregnant, breastfeeding, under 18 or taking any medication, consult a doctor before use. Stop use if adverse reactions occur.
Interactions: It is unclear whether or not PQQ interacts with any medications or not. PQQ does however, increase levels of anti-oxidants produced by the body, such as Glutathione, which may have a negative effect on certain chemo-therapeutics. If you are taking any chronic medications please or any other medication, please first speak with your doctor before adding PQQ to your supplement regime
For further information regarding any other potential drug and supplement interactions of PQQ please see the ingredient profile on Drug Bank.*
Allergy: This product does not contain any common allergens; however, it should not be used by anyone with a history of hypersensitivity to its ingredients or those taking medications that may interact with it.
Pregnancy: If pregnant, consult your health professional before using this product.
*Drug Bank is an independent website that lists potential interactions between the ingredients in PQQ and other medications and supplements. It may not, however, list all known possible interactions. If you are on any medications or supplements you feel may interact negatively with PQQ please first speak with your doctor before using this product.
Do not exceed the recommended daily dose. Food supplements should not replace a varied and balanced diet and a healthy lifestyle. If you are pregnant, breastfeeding, under 18 or taking any medication, consult a doctor before use. Stop use if adverse reactions occur.
Interactions: As of 10 November 2024, there are no known published direct interactions between Spermidine and other medications. However, this does not mean interactions do not exist. Spermidine is a supplement that can improve insulin sensitivity; if you take medications and/or other supplements to help manage your blood sugar, you should first speak with your doctor before adding Spermidine to your supplement regime.
For further information regarding any other potential drug and supplement interactions of Spermidine please see the individual ingredient profile on Drug Bank*.
Allergy: This product does not contain any common allergens; however, it should not be used by anyone with a history of hypersensitivity to its ingredients or those taking medications that may interact with it.
Pregnancy: If pregnant, consult your health professional before using this product.
*Drug Bank is an independent website that lists potential interactions between the ingredients in Spermidine and other medications and supplements. It may not, however, list all known possible interactions. If you are taking any medications or supplements you feel may interact negatively with Spermidine please first speak with your doctor before using this product.
Do not exceed the recommended daily dose. Food supplements should not replace a varied and balanced diet and a healthy lifestyle. If you are pregnant, breastfeeding, under 18 or taking any medication, consult a doctor before use. Stop use if adverse reactions occur.
Interactions: Trans-Resveratrol is known to inhibit members of the Cytochrome P450 class of enzymes. As a result, it may interfere with antiplatelet and anticoagulant medications such as Warfarin. Additionally, resveratrol is classed as a phytoestrogen, a plant molecule that can mimic the effects of oestrogen in the body. Therefore, individuals who are hormone replacement therapies should therefore consult with their doctors before adding resveratrol to their longevity protocols. If you are taking these medications or any other medication, please first speak with your doctor before adding Resveratrol to your supplement regime.
For further information regarding any other potential drug and supplement interactions of Trans-Resveratrol, please see the ingredient profile on Drug Bank.*
Allergy: This product does not contain any common allergens; however, it should not be used by anyone with a history of hypersensitivity to its ingredients or those taking medications that may interact with it.
Pregnancy: If pregnant, consult your health professional before using this product.
*Drug Bank is an independent website that lists potential interactions between the ingredients in Trans-Resveratrol and other medications and supplements. It may not, however, list all known possible interactions. If you are on any medications or supplements you feel may interact negatively with Trans-Resveratrol please first speak with your doctor before using this product.
Orders placed are shipped within 24 hours (Monday to Friday) from the UK.
Need some advice?
Customer Care | +44 (0) 1202 082 280 | support@vitality-pro.com
While individual results may vary due to personal health conditions, genetics, and lifestyle choices, we guarantee that the supplements you receive are made with ingredients of the highest purity, similar to those used in scientific studies, to ensure maximum results.
Red blood cell magnesium and chronic fatigue syndrome – Case-Control Study and Randomised Controlled Trial
Dosage: Intramuscular magnesium sulphate every week for 6 weeks
Outcome: Improvement in energy levels, emotional state, and pain
Summary: The study found that patients with chronic fatigue syndrome (CFS) have lower red cell magnesium levels. Treatment with magnesium improved symptoms such as energy, mood, and pain in CFS patients, with a significant difference compared to placebo.
Magnesium-L-threonate improves sleep quality and daytime functioning in adults with self-reported sleep problems – Randomised controlled trial
Dosage: 1 g/day magnesium L-threonate, , providing 75 mg elemental magnesium
Outcome: Daytime energy, alertness, productivity, and sleep quality
Summary: Magnesium L-threonate improved deep and REM sleep and led to higher daytime energy, mental alertness, and productivity compared with placebo, likely by supporting brain and mitochondrial energy metabolism.
Magnesium and Fibromyalgia: A Literature Review – Literature Review
Dosage: Oral magnesium typically 300–600 mg/day
Outcome: Fatigue, pain, function, and energy-related symptoms in fibromyalgia.
Summary: Some studies suggest magnesium may support cellular energy (ATP) production and reduce fatigue, but results are mixed and evidence is not definitive.
Pyrroloquinoline Quinone (PQQ): Its impact on human health and potential benefits – Narrative Review
Dosage: Human studies cited include single doses of PQQ at 0.2 mg/kg body weight; commonly studied supplemental intakes in humans are typically ~10–20 mg/day.
Outcome: Effects of PQQ on mitochondrial function, energy production, fatigue, and metabolic health.
Summary: PQQ supports mitochondrial biogenesis and antioxidant defence, which can improve cellular energy production and reduce fatigue. Human and animal data suggest PQQ may help people feel less tired by improving how efficiently cells make ATP and handle oxidative stress.
Efficacy and safety of a novel dietary pyrroloquinoline quinone disodium salt on muscle strength and physical function in healthy volunteers – Randomised, double-blind, placebo-controlled trial
Dosage: 21.5 mg/day pyrroloquinoline quinone (PQQ) disodium salt for 12 weeks
Outcome: Improved muscle strength and physical function, suggesting better energy production and reduced physical fatigue
Summary: Daily PQQ supplementation significantly improved leg strength, grip strength, and walking performance compared to placebo, with no safety issues reported, indicating improved muscular energy and reduced fatigue.
Effects of Oral Supplementation with Pyrroloquinoline Quinone on Stress, Fatigue, and Sleep – Open-label human trial
Dosage: 20 mg PQQ daily for 8 weeks
Outcome: Reduced fatigue and improved energy, mood, and sleep quality
Summary: Daily PQQ intake significantly reduced fatigue and increased feelings of energy and vigour, alongside better sleep and stress scores in adults.
Molecular basis of the ‘anti-aging’ effect of spermidine and other natural polyamines – Review
Outcome: Autophagy is the main way by which spermidine exerts health effects.
Summary: Spermidine, a natural polyamine, boosts autophagy and may also reduce inflammation, improve fat metabolism, and regulate cell growth and death by controlling the activity of the AMPK pathway to support healthy ageing.
Spermidine is essential for fasting-mediated autophagy and longevity – Review
Outcome: Fasting increased spermidine levels across species, promoting autophagy and extending lifespan through spermidine-dependent mechanisms.
Summary: This study highlights the key role of spermidine in activating autophagy during fasting. By increasing spermidine levels, fasting enhances the body’s ability to clear damaged cells, improving longevity and reducing the risk of age-related diseases. Blocking spermidine production was shown to disrupt these benefits, revealing spermidine’s essential role in fasting-mediated health improvements.
Effect of Resveratrol Supplementation on Inflammatory Markers – A Systematic Review and Meta-analysis of Randomised Controlled Trials
Dosage: Mixed
Outcome: Reduction in levels of TNF-α and hs-CRP, two markers of inflammation
Summary: This study found that taking resveratrol can help lower certain signs of inflammation in the body. This suggests resveratrol might be useful alongside other treatments for diseases linked to inflammation.
The Role and Mechanism of SIRT1 in Resveratrol-regulated Osteoblast Autophagy in Osteoporosis Rats – Animal study
Dosage: 5 mg/kg/day and 45 mg/kg/day resveratrol for 8 weeks
Outcome: Resveratrol improved bone density and promoted autophagy in bone cells through SIRT1 activation.
Summary: High-dose resveratrol activated SIRT1 and enhanced mitophagy in osteoblasts, protecting against bone loss in osteoporosis rats.
Resveratrol, an Nrf2 activator, ameliorates aging-related progressive renal injury – Experimental Animal & Cell Study
Dosage: 40 mg/kg resveratrol daily in aged mice for 6 months; 50 μM resveratrol in HK2 kidney cells (in vitro).
Outcome: Resveratrol activates Nrf2 and increases antioxidant defences, reducing oxidative stress and kidney damage linked to ageing.
Summary: Resveratrol increased Nrf2 activity and its downstream antioxidants (HO-1, NQO-1, SOD1/2), which lowered oxidative stress and improved age-related kidney damage in mice. Blocking Nrf2 stopped these protective effects, showing Nrf2 is central to resveratrol’s action.
Alex Manos’ energy support bundle is designed to aid cellular energy production by supporting the health and function of the mitochondria, cell components that work to create ATP, the energy currency that runs the human body.
Products:
● Magnesium Threonate
● PQQ
● Spermidine
● Trans Resveratrol
Magnesium is an essential cofactor for ATP synthesis and mitochondrial enzyme function. Magnesium-ATP is the biologically active form of ATP, and magnesium deficiency directly impairs oxidative phosphorylation. It stabilices mitochondrial membranes and is required for proper function of Complex I and ATP synthase. Without adequate magnesium, even abundant substrates cannot be efficiently converted to cellular energy.
PQQ promotes mitochondrial biogenesis through activation of PGC-1α signalling. PQQ supplementation has been shown to trigger energy production through ATP generation and improve mitochondrial function. PQQ protects mitochondria from oxidative damage while promoting generation of new mitochondria within aging cells—a “fountain of youth” for mitochondrial function. This dual action of protection and proliferation makes PQQ uniquely valuable for mitochondrial support.
Spermidine induces autophagy and mitophagy, essential quality control mechanisms for mitochondrial health. Spermidine is a naturally occurring polyamine that elicits geroprotection and autophagy induction across species, prolongs lifespan in multiple organisms, and postpones manifestation of age-associated disorders including cardiovascular disease and neurodegeneration in mice. Spermidine exhibits anti-inflammatory and antioxidant properties, enhances mitochondrial metabolic function and respiration, and external supplementation extends lifespan and health span across species. In aging mouse models, spermidine administration balanced mitochondrial dynamics and maintained energy for neurons through regulation of mitochondrial fusion and fission proteins, increased COX IV and ATP levels.
Trans-Resveratrol activates SIRT1 and AMPK pathways central to mitochondrial biogenesis and function. Resveratrol increases mitochondrial mass, mitochondrial DNA content, up-regulates electron transport chain protein expression, and induces mitochondrial biogenesis factors including PGC-1α, NRF-1, and TFAM. In Parkinson’s disease fibroblasts, resveratrol treatment enhanced mitochondrial oxidative function through AMPK/SIRT1/PGC-1α axis activation, increased complex I and citrate synthase activities, basal oxygen consumption, and mitochondrial ATP production while decreasing lactate, supporting a metabolic switch from glycolytic to oxidative metabolism.
Alex Manos BSc MSc NASM IFMCP is one of the few Institute for Functional Medicine Certified Practitioners in the UK. He has a master’s degree in Personalised Nutrition, for which he completed his dissertation on cortisol resistance in chronic fatigue syndrome. Alex also has a first-class degree in Nutritional Therapy and has completed Dr Siebecker’s certification in SIBO treatment.rnrnAway from his one-to-one work with clients, Alex lectures at various institutions and has been a clinical supervisor and mentor in the health and fitness industry.
Consider the following statements. If you find one or more relatable, Alex’s Mitochondrial support bundle might be the support you’ve been searching for:
We are committed to the following quality controls to ensure consistency, reliability, and transparency in every product. Our goal is to raise industry standards and give you clear reasons to trust what you’re taking.
All products are made to cGMP (current Good Manufacturing Practice) standards, the global benchmark for supplement quality. GMP standards ensure strict control over how our supplements are produced, covering everything from cleanliness to documentation and quality control. Every step is monitored to guarantee consistency and safety in every batch, so you receive the same high-quality product every time.
Created by the US FDA, GMP regulations legally require manufacturers to ensure product safety, purity, and effectiveness. GMP minimises contamination, mix-ups, and errors, protecting consumers from ineffective or unsafe products.
GMP Guidelines Overview:
At the foundation of what we offer is certainty of product quality through consistent third-party testing, specifically for purity.
In an industry where many supplement providers cannot be fully certain of their product quality, third-party testing is essential to ensure purity and safety. This process removes uncertainty, so you can be confident that you’re taking supplements that are both safe and effective.
Every active ingredient in every batch of vitalityPRO products is independently tested by accredited laboratories to ensure unbiased analysis of purity.
In the case of collagen, we test for total protein content. Since collagen is not a single compound but a group of proteins composed of amino acids, there is no direct test for ‘collagen’ itself. Measuring total protein provides an indirect but reliable indicator of collagen content.
Additional third-party testing screens for contaminants such as heavy metals, pesticides, and microbes, ensuring that each product is safe for consumption. Although certificates are provided by the manufacturer, this independent validation goes beyond standard testing, adding an extra layer of quality control.
Independent third-party testing ensures that you receive reliable, high-quality products every time.
ISO 9001:2015 standards are an internationally recognised framework for effective quality management. This accreditation means we follow a structured system of continuous improvement, always refining our processes to enhance product consistency and customer satisfaction. ISO accreditation ensures that every aspect of our operations—from production to customer service—is optimised. This means better oversight, reduced risk of errors, and a clear focus on delivering consistent results.
ISO 9001:2015 accreditation highlights a commitment to quality, customer satisfaction, and continuous improvement.
We believe you should have full clarity about what you’re putting in your body and the steps we take to ensure the quality of our supplements. That’s why we are transparent and open about every part of our process.
Transparency means we share all the details that matter—how our products are made, tested, and verified. From publishing third-party test results to offering clear ingredient labels, we provide you with the information you need to make informed choices about your supplements. Nothing is hidden, and every product comes with full accountability.
If you are new to these products we suggest that you layer them in one at a time to see how you tolerate each one. There is no right order however we suggest that you follow the guidelines under the ‘recommended use’ section of this page.
Creatine is an excellent addition to this bundle. Alex chose not to include as he finds the other products in this bundle are effective at helping to support mitochondria. If you would like to add creatine to this bundle you are welcome to do so and can find vitalityPRO’s Creapure product here.
Mould illness is a complex disease that requires both a holistic approach and time to recover.We recommend that you trial the bundle for at least 60 days. That said many people do start to notice an uptick in energy after a few weeks of using the products.
Mitochondria are your cells’ energy powerhouses. When they malfunction, every system suffers—especially high-energy organs like the brain, muscles, and heart. Supporting mitochondrial health requires providing the right fuel, nutrients, and signals to optimise energy production.
Circadian Rhythm
Mitochondria function according to circadian rhythms—their efficiency peaks and troughs throughout the day. Morning light exposure and consistent sleep-wake timing optimise mitochondrial biogenesis (creation of new mitochondria) and function. Poor circadian health directly impairs cellular energy production and increases oxidative stress. Prioritise 7-9 hours of quality sleep when mitochondrial repair and regeneration peak.
Diet: Local, Seasonal Whole Foods
Mitochondria require specific nutrients to produce ATP (cellular energy). Whole foods provide these in bioavailable forms: B vitamins (energy metabolism), magnesium (ATP production), CoQ10 (electron transport chain), and iron (oxygen transport). Seasonal produce offers peak nutrient content. Minimise processed foods, which lack these critical cofactors and burden mitochondria with inflammatory compounds. A Meditaerean diet is a good framework to operate from.
Omega-3 Fats
Omega-3s are incorporated into mitochondrial membranes, improving their fluidity and function. They also reduce oxidative stress and inflammation that damage mitochondria. Include fatty fish, grass-fed meat, pastured eggs, and plant sources like walnuts and flaxseeds. Adequate omega-3 intake supports mitochondrial biogenesis.
Polyphenols
Polyphenols activate cellular pathways (like PGC-1α) that stimulate mitochondrial biogenesis and protect existing mitochondria from oxidative damage. Green tea (EGCG), resveratrol (berries, grapes), quercetin (onions, apples), and curcumin (turmeric) are particularly beneficial. These compounds essentially signal your body to make more, healthier mitochondria.
Dietary Diversity
Different foods provide different mitochondrial cofactors. Variety ensures comprehensive nutrient coverage: leafy greens (magnesium, folate), organ meats (CoQ10, B vitamins), nuts and seeds
(vitamin E, selenium), colourful vegetables (antioxidants). A diverse gut microbiome also produces metabolites like butyrate that fuel mitochondria, particularly in the gut lining.
Exercise: Non-Negotiable for Mitochondrial Health
Exercise is the most powerful stimulus for mitochondrial biogenesis—it signals your body to create new, efficient mitochondria. However, the approach must match your current capacity. For those with significant dysfunction, start with very gentle, short-duration activities: 5-10 minutes of walking, light stretching, or low-resistance cycling. The key is consistency, not intensity initially. As tolerance builds, gradually incorporate higher-intensity intervals, which particularly stimulate mitochondrial adaptation. Both aerobic exercise (builds mitochondrial density) and resistance training (builds muscle mass and metabolic capacity) are valuable. Without exercise, mitochondrial recovery will be limited—movement is the primary signal that tells your body to invest in energy infrastructure. If starting from severe dysfunction, increase duration before intensity, and allow adequate recovery between sessions.
Gut Health
The gut microbiome profoundly influences mitochondrial function through multiple mechanisms: producing short-chain fatty acids that fuel colonocytes’ mitochondria, modulating systemic inflammation, synthesising vitamins (B12, K2), and influencing nutrient absorption. Dysbiosis can impair mitochondrial function throughout the body. Support gut health with fermented foods, diverse fiber sources, and adequate hydration. Addressing gut health often yields improvements in systemic energy levels.
Stress Management & Nervous System Support
Chronic stress directly damages mitochondria through cortisol dysregulation and oxidative stress. It also diverts resources from repair to survival mode. Practice daily stress reduction: meditation, breathwork, time in nature, or activities that genuinely restore you. Sleep quality is critical—mitochondrial repair peaks during deep sleep. Consider adaptogenic herbs (ashwagandha, rhodiola) under practitioner guidance. Balancing your nervous system creates the internal environment for mitochondrial healing.
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