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For best results, take 5 grams of creatine in the morning or evening. Creatine is water soluble meaning it can be taken with or without food.
If you experience nausea when taking Creatine on an empty stomach, we suggest you take it with a meal.
It was previously thought that creatine required a loading phase. New evidence now indicates that saturation of muscle cells with creatine can be accomplished without such a phase.
| Amount Per Capsule | Amount | %NRV |
|---|---|---|
| Creatine Monohydrate | 5 grams | * |
Nutrient Reference Value not established*
Suitable for vegans. Contains no GMOs, fillers, common allergens, artificial colours, preservatives or flavours.
Date · Batch # · Results
Purity results include Heavy Metals
Previous results:
December 2024 · 2400650
100% Purity
and Microbiology
Testing is carried out by Certified Labs (formerly Micro Quality Labs).
To maintain the potency and quality of your Creatine supplements, store them in a cool (20°C-25°C), dry place and away from light.
Manufacturing: All products are made to GMP standards and have been quality-managed in accordance with the UK standard ISO 9001:2015.
Third-party tested: To ensure the highest purity and maximum effectiveness, each new batch of products undergoes third-party testing by ISO 17025 accreditated Certified Labs (formerly Micro Quality Labs). You can view all testing certificates at www.vitality-pro.com/batch-testing.
Do not exceed the recommended daily dose. Food supplements should not replace a varied and balanced diet and a healthy lifestyle. If you are pregnant, breastfeeding, under 18 or taking any medication, consult a doctor before use. Stop use if adverse reactions occur.
Interactions: Combining creatine with drugs that impact kidney function, such as cimetidine (used for heartburn), probenecid (for gout), and certain nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen, may increase the risk of kidney damage. Additionally, using creatine alongside diuretics may lead to dehydration and put strain on the kidneys.
For further information regarding any other potential drug and supplement interactions of Creatine, please see the ingredient profile on Drug Bank.*
Allergy: This product does not contain any common allergens; however, it should not be used by anyone with a history of hypersensitivity to its ingredients or those taking medications that may interact with it.
Pregnancy: If pregnant, consult your health professional before using this product.
*Drug Bank is an independent website that lists potential interactions between the ingredients in Creatine and other medications and supplements. It may not, however, list all known possible interactions. If you are on any medications or supplements you feel may interact negatively with Creatine please first speak with your doctor before using this product.
Creatine is a naturally occurring compound that plays an important role in energy production. Supplementing with creatine has been shown to enhance muscle strength and power, improve exercise performance and support cognitive function.
For best results, take 5 grams of creatine in the morning or evening. Creatine is water soluble meaning it can be taken with or without food.
If you experience nausea when taking Creatine on an empty stomach, we suggest you take it with a meal.
It was previously thought that creatine required a loading phase. New evidence now indicates that saturation of muscle cells with creatine can be accomplished without such a phase.
| Amount Per Capsule | Amount | %NRV |
|---|---|---|
| Creatine Monohydrate | 5 grams | * |
Nutrient Reference Value not established*
Suitable for vegans. Contains no GMOs, fillers, common allergens, artificial colours, preservatives or flavours.
Date · Batch # · Results
Purity results include Heavy Metals
Previous results:
December 2024 · 2400650
100% Purity
and Microbiology
Testing is carried out by Certified Labs (formerly Micro Quality Labs).
To maintain the potency and quality of your Creatine supplements, store them in a cool (20°C-25°C), dry place and away from light.
Manufacturing: All products are made to GMP standards and have been quality-managed in accordance with the UK standard ISO 9001:2015.
Third-party tested: To ensure the highest purity and maximum effectiveness, each new batch of products undergoes third-party testing by ISO 17025 accreditated Certified Labs (formerly Micro Quality Labs). You can view all testing certificates at www.vitality-pro.com/batch-testing.
Do not exceed the recommended daily dose. Food supplements should not replace a varied and balanced diet and a healthy lifestyle. If you are pregnant, breastfeeding, under 18 or taking any medication, consult a doctor before use. Stop use if adverse reactions occur.
Interactions: Combining creatine with drugs that impact kidney function, such as cimetidine (used for heartburn), probenecid (for gout), and certain nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen, may increase the risk of kidney damage. Additionally, using creatine alongside diuretics may lead to dehydration and put strain on the kidneys.
For further information regarding any other potential drug and supplement interactions of Creatine, please see the ingredient profile on Drug Bank.*
Allergy: This product does not contain any common allergens; however, it should not be used by anyone with a history of hypersensitivity to its ingredients or those taking medications that may interact with it.
Pregnancy: If pregnant, consult your health professional before using this product.
*Drug Bank is an independent website that lists potential interactions between the ingredients in Creatine and other medications and supplements. It may not, however, list all known possible interactions. If you are on any medications or supplements you feel may interact negatively with Creatine please first speak with your doctor before using this product.
Orders placed are shipped within 24 hours (Monday to Friday) from the UK.
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While individual results may vary due to personal health conditions, genetics, and lifestyle choices, we guarantee that the supplements you receive are made with ingredients of the highest purity, similar to those used in scientific studies, to ensure maximum results.
Creatine in Health and Disease – Systematic Review
Dosage: Creatine supplementation varied between 2-3 g/day for maintenance to higher doses such as 20 g/day for specific protocols.
Outcome: Creatine supports cellular energy, muscle strength, cognitive function, glucose management.
Summary: Creatine supplementation offers broad health benefits, including supporting energy metabolism, muscle and bone health, cognition and even potential therapeutic effects for chronic diseases and injury recovery.
Methylation demand and homocysteine metabolism: effects of dietary provision of creatine and guanidinoacetate– Animal Study
Dosage: 0.4% creatine monohydrate or 0.36% guanidinoacetate (GAA) in diet for 2 weeks.
Outcome: Creatine supplementation decreased plasma homocysteine by 27%; GAA increased it by 49%.
Summary: Creatine supplementation reduced the demand for methyl groups, leading to lower homocysteine levels, while GAA increased methylation demand, raising homocysteine.
Creatine Supplementation and Brain Health – Review
Dosage: Ranges from 2 g/day to 20 g/day, depending on the study duration (1 to 8 weeks).
Outcome: Creatine supplementation may improve brain health by supporting cognitive function, especially under stress or in conditions with brain creatine deficits.
Summary: Creatine shows promise for enhancing cognitive performance and recovery from brain injuries or stress.
The effects of creatine supplementation on cognitive function in adults: a systematic review and meta-analysis – and Meta-Analysis
Dosage: Ranged from 3 g/day to 20 g/day, with durations from 7 days to 18 months
Outcome: Creatine improved memory, attention time, and information processing speed but had no significant impact on overall cognitive or executive function.
Summary: Creatine supplementation supports brain energy metabolism, enhancing memory and processing speed, particularly in younger adults and those with certain illnesses.
Creatine Supplementation for Muscle Growth: A Scoping Review of Randomized Clinical Trials from 2012 to 2021 – Review
Dosage: Varied dosages
Outcome: Creatine supports muscle strength and lean mass gain, particularly in healthy, young, trained individuals when combined with exercise.
Summary: Creatine is effective for boosting exercise performance and muscle growth in healthy young populations with training.
Creatine supplementation and endurance performance: surges and sprints to win the race’ lifespan – Review
Dosage: 20 g/day for 5-7 days loading, followed by 3-5 g/day maintenance.
Outcome: Enhanced anaerobic performance, improved high-intensity efforts, and potential benefits for endurance activities requiring surges or sprints.
Summary: Creatine improves endurance performance during activities with multiple surges or finishing sprints by enhancing ATP regeneration, glycogen storage, and buffering capacity.
Creatine is a natural compound that is produced by the body from the amino acids, glycine and arginine. It is primarily found in skeletal muscle, with smaller amounts in the brain, heart, and other tissues. Dietary creatine is primarily obtained from animal-based foods—red meat, poultry, and fish being among the richest sources.
Pürest Creatine™ is NNB Nutrition’s branded creatine monohydrate. Creatine monohydrate is the most widely studied form of creatine and is proven to be safe and effective. Pürest Creatine™ is manufactured to stringent purity specifications, with third-party testing showing no detectable DCD or DHT and exceptionally low levels of other common creatine impurities.
Creatine primary role is to maintain the cycle of regenerating cellular energy known as ATP, the body’s main energy source and provides energy to cells of the body, quickly and when needed.
When the body uses the bodies main source of cellular energy known as ATP – it depletes into ADP. Creatine (as phosphocreatine) quickly adds the phosphate group to ADP, turning it back into ATP. This action helps reduce the strain on mitochondria to constantly produce new ATP for use by the body as energy.
Creatine comes in two forms: free-form creatine and phosphocreatine. Phosphocreatine is the “charged” form because it carries a phosphate group that stores energy. When this phosphate group is transferred to ADP to form ATP, phosphocreatine reverts back to free creatine. Free creatine is then available to pick up another phosphate group and be recharged with energy again. Without the phosphate group, creatine primarily serves as the precursor and reserve that can be quickly converted into phosphocreatine when needed.
Creatine also acts as an antioxidant and helps to reduce high levels of oxidative stress and lower inflammation by scavenging harmful molecules called free radicals.
In the brain, creatine enhances cognitive function by increasing energy availability to brain cells called neurons. It does this by increasing levels of ATP, ensuring that neurons have sufficient energy to perform tasks such as signal transmission. Additionally, studies have observed that creatine can improve memory, attention, and overall mental performance, especially during periods of sleep deprivation or mental fatigue.
As a result of these mechanisms, creatine has been studied and shown to improve brain function, fatigue, exercise performance and recovery.
Creatine is also has osmolyte properties which are molecules that help regulate the balance of water in and out of cells maintain cellular hydration, which is important for proper cellular function and stability, and nutrient absorption. However, its primary role is in energy metabolism, where it is converted to phosphocreatine to rapidly regenerate ATP during high-energy demands.
Finally, when the body creates creatine it consumes significant amounts of methyl groups. These are chemical groups that are required for various biochemical processes in the body. By supplementing with creatine, the body’s need to produce these groups decreases meaning more methyl groups are available for other essential functions like DNA repair and neurochemical production
As we age, energy production becomes crucial for maintaining the health of cells, muscle mass and cognitive function. By supporting the mitochondria and the cells of the body, creatine may help counteract age related muscle loss. Research also shows that creatine may act as a neuroprotective agent and support cognitive function. Although more studies are needed to confirm these benefits in humans, these findings highlight creatine’s promising role in promoting healthy aging and potentially extending healthspan.
Consider the following statements. If you find one or more relatable, Creatine might be the support you’ve been searching for:
We are committed to the following quality controls to ensure consistency, reliability, and transparency in every product. Our goal is to raise industry standards and give you clear reasons to trust what you’re taking.
All products are made to cGMP (current Good Manufacturing Practice) standards, the global benchmark for supplement quality. GMP standards ensure strict control over how our supplements are produced, covering everything from cleanliness to documentation and quality control. Every step is monitored to guarantee consistency and safety in every batch, so you receive the same high-quality product every time.
Created by the US FDA, GMP regulations legally require manufacturers to ensure product safety, purity, and effectiveness. GMP minimises contamination, mix-ups, and errors, protecting consumers from ineffective or unsafe products.
GMP Guidelines Overview:
At the foundation of what we offer is certainty of product quality through consistent third-party testing, specifically for purity.
In an industry where many supplement providers cannot be fully certain of their product quality, third-party testing is essential to ensure purity and safety. This process removes uncertainty, so you can be confident that you’re taking supplements that are both safe and effective.
Every active ingredient in every batch of vitalityPRO products is independently tested by accredited laboratories to ensure unbiased analysis of purity.
Additional third-party testing screens for contaminants such as heavy metals, pesticides, and microbes, ensuring that each product is safe for consumption. Although certificates are provided by the manufacturer, this independent validation goes beyond standard testing, adding an extra layer of quality control.
Independent third-party testing ensures that you receive reliable, high-quality products every time.
ISO 9001:2015 standards are an internationally recognised framework for effective quality management. This accreditation means we follow a structured system of continuous improvement, always refining our processes to enhance product consistency and customer satisfaction. ISO accreditation ensures that every aspect of our operations—from production to customer service—is optimised. This means better oversight, reduced risk of errors, and a clear focus on delivering consistent results.
ISO 9001:2015 accreditation highlights a commitment to quality, customer satisfaction, and continuous improvement.
We believe you should have full clarity about what you’re putting in your body and the steps we take to ensure the quality of our supplements. That’s why we are transparent and open about every part of our process.
Transparency means we share all the details that matter—how our products are made, tested, and verified. From publishing third-party test results to offering clear ingredient labels, we provide you with the information you need to make informed choices about your supplements. Nothing is hidden, and every product comes with full accountability.
A loading dose is an initial, higher amount of creatine taken over a short period to rapidly saturate the muscles with creatine. However, recent research indicates that this approach isn’t necessary. Studies have shown that a consistent daily dose—often referred to as a maintenance dose—can effectively raise and saturate muscle creatine levels over time without the need for an initial loading phase. This not only minimises potential side effects, such as gastrointestinal discomfort, but also simplifies the supplementation protocol while still providing proven benefits.
Creatine monohydrate is the most widely studied and scientifically supported form of creatine. Pürest Creatine™ is produced to strict purity standards and independently tested to verify low levels of common creatine impurities, giving consumers confidence in the quality and consistency of every batch.
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